Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216783 | 0.95 | PPARD (0.35) | PPARDPARP14PARP10KMT2AALOX5 | |
| SCHEMBL7217018 | 0.92 | PARP14 (0.36) | PARP14PARP10ALOX5PTGDR2L3MBTL1 | |
| SCHEMBL7218231 | 0.92 | MAPT (0.34) | PPARDPARP14PARP10KMT2AALOX5 | |
| SCHEMBL7216417 | 0.92 | PPARD (0.42) | PPARDKMT2AALOX5PPARGPPARA | |
| SCHEMBL7218190 | 0.91 | PPARD (0.43) | PPARDKMT2AALOX5PPARGPPARA | |
| SCHEMBL7216335 | 0.89 | PARP10 (0.45) | PARP14PARP10KMT2AL3MBTL1KDM4E | |
| SCHEMBL7222714 | 0.86 | FFAR4 (0.32) | PTGDR2FFAR1 | |
| SCHEMBL7218151 | 0.86 | PPARD (0.34) | PPARDPARP14PARP10KMT2AL3MBTL1 | |
| SCHEMBL7216554 | 0.84 | HRH3 (0.43) | KMT2AALOX5RXRAL3MBTL1 | |
| SCHEMBL7218103 | 0.83 | NR4A2 (0.49) | KMT2AALOX5SLC26A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627651-B1 | Exhibiting preventive and therapeutic effects against HIV infectious diseases wherein R1 is an optionally substituted five- or six-membered ring group; X1 is a free valency or the like; W is a divalent group and inhibitors of HIV (human | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-30 | — | — | US | disclosed |
| EP-1182195-A1 | CYCLIC COMPOUNDS AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |