Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.32 |
| ▸ | HRH2 | P25021 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216783 | 0.94 | PPARD (0.35) | MAPTLMNAPTGDR2PPARDPARP14 | |
| SCHEMBL7215840 | 0.92 | PPARD (0.37) | PTGDR2PPARDPARP14PARP10L3MBTL1 | |
| SCHEMBL7217018 | 0.92 | PARP14 (0.36) | MAPTLMNAPTGDR2PARP14PARP10 | |
| SCHEMBL7218226 | 0.91 | PARP14 (0.34) | MAPTLMNAPTGDR2PPARDPARP14 | |
| SCHEMBL7216335 | 0.87 | PARP10 (0.45) | MAPTPARP14PARP10L3MBTL1KMT2A | |
| SCHEMBL7218151 | 0.85 | PPARD (0.34) | MAPTLMNAPPARDPARP14PARP10 | |
| SCHEMBL7221445 | 0.85 | FFAR1 (0.39) | ALOX5FFAR1POLB | |
| SCHEMBL7216417 | 0.84 | PPARD (0.42) | PPARDALOX5KMT2A | |
| SCHEMBL7218190 | 0.83 | PPARD (0.43) | MAPTPPARDL3MBTL1ALOX5KMT2A | |
| SCHEMBL7218091 | 0.83 | PARP10 (0.37) | MAPTLMNAPARP14PARP10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627651-B1 | Exhibiting preventive and therapeutic effects against HIV infectious diseases wherein R1 is an optionally substituted five- or six-membered ring group; X1 is a free valency or the like; W is a divalent group and inhibitors of HIV (human | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-30 | — | — | US | disclosed |
| EP-1182195-A1 | CYCLIC COMPOUNDS AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |