Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215840 | 0.92 | PPARD (0.37) | PARP14PARP10KDM4EPTGDR2ALOX5 | |
| SCHEMBL7218231 | 0.92 | MAPT (0.34) | PARP14PARP10PTGDR2ALOX5LMNA | |
| SCHEMBL7216335 | 0.91 | PARP10 (0.45) | PARP14PARP10MRGPRX4KDM4EL3MBTL1 | |
| SCHEMBL7218091 | 0.90 | PARP10 (0.37) | PARP14PARP10KDM4ETP53LMNA | |
| SCHEMBL7216783 | 0.89 | PPARD (0.35) | PARP14PARP10KDM4EPTGDR2ALOX5 | |
| SCHEMBL7218103 | 0.85 | NR4A2 (0.49) | ALOX5SLC26A4GLANPC1NR4A2 | |
| SCHEMBL7222219 | 0.84 | S1PR1 (0.41) | MRGPRX4KDM4EALOX5TP53LMNA | |
| SCHEMBL7216417 | 0.84 | PPARD (0.42) | ALOX5 | |
| SCHEMBL7223004 | 0.84 | SMN1; SMN2 (0.43) | MRGPRX4KDM4EALOX5TP53LMNA | |
| SCHEMBL7221400 | 0.83 | SMN1; SMN2 (0.48) | MRGPRX4ALOX5TP53LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627651-B1 | Exhibiting preventive and therapeutic effects against HIV infectious diseases wherein R1 is an optionally substituted five- or six-membered ring group; X1 is a free valency or the like; W is a divalent group and inhibitors of HIV (human | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-30 | — | — | US | disclosed |
| EP-1182195-A1 | CYCLIC COMPOUNDS AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |