Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045775 | 0.75 | HTR2A (0.34) | HTR2A | |
| Hydrochloric Acid SCHEMBL4880315 | 0.72 | GPR3 (0.44) | — | |
| SCHEMBL9838782 | 0.72 | HTR2A (0.32) | HTR2A | |
| SCHEMBL6337587 | 0.68 | HTR2A (0.42) | HTR2A | |
| Hydrochloric Acid SCHEMBL675736 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL29281382 | 0.64 | HTR2A (0.34) | HTR2A | |
| SCHEMBL28738009 | 0.64 | HTR2A (0.42) | HTR2A | |
| Hydrochloric Acid SCHEMBL29573304 | 0.63 | BRD4 (0.34) | HTR2A | |
| Hydrochloric Acid SCHEMBL4740946 | 0.63 | HTR6 (0.31) | HTR2A | |
| SCHEMBL4652559 | 0.61 | HTR2A (0.38) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617466-B1 | Having a heteroatom ligand containing an element with a coordination number of three from Group V A or a coordination number of two from Group VI A attached to the ring through a hydrocarbylene, silane or germanium group | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-09-09 | — | — | US | disclosed |
| US-5844055-A | Ethylene/branched olefin copolymers | EXXON CHEMICAL PATENTS INC. (US) | 1998-12-01 | — | — | US | disclosed |
| EP-0641362-B1 | ETHYLENE/BRANCHED OLEFIN COPOLYMERS | EXXON CHEMICAL PATENTS INC (US) | 1998-11-11 | — | — | EP | disclosed |
| US-5475075-A | High molecular weight blends | EXXON CHEMICAL PATENTS INC. (US) | 1995-12-12 | — | — | US | disclosed |
| EP-0671404-A2 | Monocyclopentadienyl transition metal olefin polymerization catalysts | EXXON CHEMICAL PATENTS INC. (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5444145-A | High molecular weight polymers with narrow molecular weight distribution, high strength, toughness | EXXON CHEMICAL PATENTS INC. (US) | 1995-08-22 | — | — | US | disclosed |
| EP-0643066-A2 | Monocyclopentadienyl transition metal olefin polymerization catalysts | EXXON CHEMICAL PATENTS INC. (US) | 1995-03-15 | — | — | EP | disclosed |
| EP-0641362-A1 | ETHYLENE/BRANCHED OLEFIN COPOLYMERS | EXXON CHEMICAL PATENTS INC. (US) | 1995-03-08 | — | — | EP | disclosed |
| EP-0616618-A1 | ETHYLENE/LONGER ALPHA-OLEFIN COPOLYMERS. | EXXON CHEMICAL PATENTS INC (US) | 1994-09-28 | — | — | EP | disclosed |
| WO-1993021242-A1 | ETHYLENE/BRANCHED OLEFIN COPOLYMERS | EXXON CHEMICAL PATENTS INC. (US) | 1993-10-28 | — | — | WO | disclosed |
| WO-1993012151-A1 | ETHYLENE/LONGER ALPHA-OLEFIN COPOLYMERS | EXXON CHEMICAL PATENTS INC. (US) | 1993-06-24 | — | — | WO | disclosed |
| US-5096867-A | Polymer products of high molecular weight and narrow molecular weight distribution using small amounts of an alumoxane with the titanium complex | EXXON CHEMICAL PATENTS INC. (US) | 1992-03-17 | — | — | US | disclosed |