Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL193449 | 0.86 | TDP1 (0.52) | TDP1LMNABLMSLC6A6CYP2C19 | |
| Sulfuric Acid SCHEMBL27929434 | 0.86 | TDP1 (0.75) | TDP1LMNABLMALOX15PMP22 | |
| Sulfuric Acid SCHEMBL421211 | 0.86 | TDP1 (0.75) | TDP1LMNABLMALOX15PMP22 | |
| Sulfuric Acid SCHEMBL27615797 | 0.86 | TDP1 (0.75) | TDP1LMNABLMALOX15PMP22 | |
| SCHEMBL27474859 | 0.84 | TDP1 (0.50) | TDP1LMNABLMSLC6A6CYP2C19 | |
| Sulfuric Acid SCHEMBL25289160 | 0.83 | TDP1 (0.71) | TDP1LMNABLMALOX15PMP22 | |
| SCHEMBL723932 | 0.83 | TDP1 (0.71) | TDP1LMNABLMALOX15PMP22 | |
| Sulfuric Acid SCHEMBL28014011 | 0.83 | TDP1 (0.71) | TDP1LMNABLMALOX15PMP22 | |
| Sulfuric Acid SCHEMBL28014012 | 0.83 | TDP1 (0.71) | TDP1LMNABLMALOX15PMP22 | |
| Propane SCHEMBL22974974 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3398973-B1 | METHOD FOR PRODUCING COPOLYMER | NIPPON CATALYTIC CHEM IND (JP) | 2020-04-01 | — | — | EP | disclosed |
| US-10570233-B2 | Method for producing copolymer | NIPPON SHOKUBAI CO., LTD. (JP) | 2020-02-25 | — | — | US | disclosed |
| US-20190210921-A1 | ADDITIVE FOR CEMENT COMPOSITION AND CEMENT COMPOSITION | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 2019-07-11 | — | — | US | disclosed |
| CN-109923087-A | Cement composition additive and cement composition | 日本制纸株式会社 | 2019-06-21 | — | — | CN | disclosed |
| US-20190127504-A1 | METHOD FOR PRODUCING COPOLYMER | NIPPON SHOKUBAI CO., LTD. (JP) | 2019-05-02 | — | — | US | disclosed |
| CN-109641395-A | The manufacturing method of ink-jet 3D printer photo-curable backing material composition, ink-jet 3D printer ink, ink-jet 3D printer print cartridge, the manufacturing method of backing material and light chisel object | 株式会社日本触媒 | 2019-04-16 | — | — | CN | disclosed |
| CN-109641201-A | Formed gel product and sintered article prepared therefrom | 3M创新有限公司 | 2019-04-16 | — | — | CN | disclosed |
| US-10227258-B2 | Shrinkage-reducing agent for hydraulic material | NIPPON SHOKUBAI CO., LTD. (JP) | 2019-03-12 | — | — | US | disclosed |
| US-10208203-B2 | Monomer composition containing unsaturated polyalkylene glycol ether-based monomer, method for producing composition thereof, polymer obtained using composition thereof, and method for producing polymer thereof | NIPPON SHOKUBAI CO., LTD. (JP) | 2019-02-19 | — | — | US | disclosed |
| EP-3398973-A1 | METHOD FOR PRODUCING COPOLYMER | Nippon Shokubai Co., Ltd. (JP) | 2018-11-07 | — | — | EP | disclosed |
| CN-1537126-A | Polycarboxylic acid type copolymer, and preparation method and use thereof | 株式会社日本触媒 | 2004-10-13 | — | — | CN | disclosed |
| US-6733941-B1 | ETHYLENE POLYMER, PARAFFIN WAX AND BINDER; LOW TEMPERATURE FIXATION, OFFSET RESISTANCE, PRESERVING IMAGE QUALITY | MITSUI CHEMICALS, INC. (JP) | 2004-05-11 | — | — | US | disclosed |
| CN-1148329-C | Cement dispersant agent and cement compsn. using same | 株式会社日本触媒 | 2004-05-05 | — | — | CN | disclosed |
| US-20040024152-A1 | Gas hydrate formation inhibitor and method for inhibiting gas hydrate formation with the same | MITSUBISHI RAYON CO., LTD. (JP) | 2004-02-05 | — | — | US | disclosed |
| US-20030130454-A1 | Process for producing amphipathic polymers | MITSUBISHI RAYON CO., LTD. | 2003-07-10 | — | — | US | disclosed |
| CN-1412145-A | Cement dispersant, method for producing same, and cement composition using same | NIPPON CATALYTIC CHEM IND (JP) | 2003-04-23 | — | — | CN | disclosed |
| CN-1390319-A | Resin composition for toner and toner | MITSUI CHEMICALS INC (JP) | 2003-01-08 | — | — | CN | disclosed |
| EP-1262838-A1 | RESIN COMPOSITION FOR TONER AND TONER | Mitsui Chemicals, Inc. (JP) | 2002-12-04 | — | — | EP | disclosed |
| CN-1343642-A | Cement dispersant agent and cement compsn. using same | NIPPON CATALYTIC CHEM IND (JP) | 2002-04-10 | — | — | CN | disclosed |
| CN-1199607-A | Hair cosmetics | SHOWA DENKO KK (JP) | 1998-11-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10208203-B2 | Monomer composition containing unsaturated polyalkylene glycol ether-based monomer, method for producing composition thereof, polymer obtained using composition thereof, and method for producing polymer thereof | ALOX12, ALOX15, ALOX15B | TDP1 2163/4885LMNA 1927/4885BLM 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.