Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.68 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.68 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.68 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.52 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11994154 | 0.86 | CHRNB2 (0.64) | CHRNB2CHRNA4CHRNB4CHRNA3HTT | |
| SCHEMBL2605696 | 0.85 | KAT6A (0.56) | CHRNB2CHRNA4CHRNB4CHRNA3HTT | |
| SCHEMBL11007801 | 0.85 | CHRNB2 (0.72) | CHRNB2CHRNA4CHRNB4CHRNA3HTT | |
| SCHEMBL11583760 | 0.83 | THRB (0.53) | CHRNB2CHRNA4CHRNB4CHRNA3HTT | |
| SCHEMBL27980137 | 0.83 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRNB4CHRNA3HTT | |
| SCHEMBL26417076 | 0.82 | HTT (0.64) | HTTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL31483721 | 0.82 | HTT (0.64) | HTTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL8841217 | 0.82 | CHRNB2 (0.68) | CHRNB2CHRNA4CHRNB4CHRNA3HTT | |
| SCHEMBL1649572 | 0.82 | CHRNB2 (0.68) | CHRNB2CHRNA4CHRNB4CHRNA3HTT | |
| SCHEMBL8947154 | 0.80 | CHRNB2 (0.60) | CHRNB2CHRNA4CHRNB4CHRNA3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669830-A4 | SUBSTITUTED DIPEPTIDE ANALOGS PROMOTE RELEASE OF GROWTH HORMONE. | MERCK & CO INC (US) | 1997-02-26 | — | — | EP | claimed |
| EP-0669830-A1 | SUBSTITUTED DIPEPTIDE ANALOGS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO. INC. (US) | 1995-09-06 | — | — | EP | claimed |
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
| CN-100415750-C | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2008-09-03 | — | — | CN | disclosed |
| CN-1772749-A | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2006-05-17 | — | — | CN | disclosed |
| CN-1239495-C | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 2006-02-01 | — | — | CN | disclosed |
| CN-1636457-A | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2005-07-13 | — | — | CN | disclosed |
| CN-1188420-C | Fungicides for control of take-all disease of plants | MONSANTO CO (US) | 2005-02-09 | — | — | CN | disclosed |
| CN-1188419-C | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 2005-02-09 | — | — | CN | disclosed |
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | disclosed |
| US-6410558-B1 | USING INDOLE OR QUINOLINE COMPOUND | MONSANTO TECHNOLOGY LLC | 2002-06-25 | — | — | US | disclosed |
| CN-1043835-C | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 1999-06-30 | — | — | CN | disclosed |
| US-5849723-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5834447-A | THIOPHENE DERIVATIVES | MONSANTO COMPANY (US) | 1998-11-10 | — | — | US | disclosed |
| US-5811411-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5705513-A | HETEROCYCLIC FUNGICIDES WITH PYRIDINE OR FURAN RINGS | MONSANTO COMPANY (US) | 1998-01-06 | — | — | US | disclosed |
| US-5693667-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| CN-1085221-A | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 1994-04-13 | — | — | CN | disclosed |
| WO-1993007751-A1 | FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO COMPANY (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0538231-A1 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | EPHX1, EPHX2, EPX | CHRNB2 3917/4885CHRNA4 4214/4885CHRNB4 3841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.