Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A2 | O00482 | 1/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.41 |
| ▸ | GLRB | P48167 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7225441 | 0.82 | NR5A2 (0.42) | NR5A2NR5A1GLRA3GLRBALOX5 | |
| SCHEMBL6466602 | 0.75 | GLRA3 (0.57) | NR5A2NR5A1GLRA3GLRBALOX5 | |
| SCHEMBL14825538 | 0.75 | GLRA3 (0.42) | NR5A2NR5A1GLRA3GLRBALDH1A1 | |
| SCHEMBL14696539 | 0.75 | POLB (0.45) | POLBAPEX1ALDH1A1GAAHDAC1 | |
| SCHEMBL7223640 | 0.74 | KCNK9 (0.55) | ALOX5PTGS2POLBALDH1A1GAA | |
| SCHEMBL14988234 | 0.74 | GLRA3 (0.41) | NR5A2NR5A1GLRA3GLRBPOLB | |
| SCHEMBL28419884 | 0.74 | GLRA3 (0.55) | NR5A2NR5A1GLRA3GLRBALOX5 | |
| SCHEMBL7219598 | 0.72 | GLRA3 (0.39) | NR5A2NR5A1GLRA3GLRBALOX5 | |
| SCHEMBL7217357 | 0.71 | LMNA (0.64) | GAASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL14696710 | 0.71 | POLB (0.41) | POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |