Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7832821 | 0.86 | KDM4E (0.32) | KDM4ECYP2A6ALDH1A1HPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL6466483 | 0.82 | ALDH1A1 (0.36) | KDM4ECYP2A6ALDH1A1CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL7725653 | 0.79 | KDM4E (0.34) | KDM4ECYP2A6ALDH1A1CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL6463028 | 0.79 | KDM4E (0.34) | KDM4ECYP2A6ALDH1A1CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL247996 | 0.79 | KDM4E (0.34) | KDM4ECYP2A6ALDH1A1CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL19520611 | 0.79 | KDM4E (0.34) | KDM4ECYP2A6ALDH1A1CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL338847 | 0.79 | KDM4E (0.37) | KDM4ECYP2A6ALDH1A1CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL5702868 | 0.79 | KDM4E (0.38) | KDM4ECYP2A6ALDH1A1CYP1A2TSHR | |
| Ethane SCHEMBL8633166 | 0.78 | ALDH1A1 (0.34) | KDM4ECYP2A6ALDH1A1CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL5702780 | 0.76 | KDM4E (0.33) | KDM4ECYP2A6ALDH1A1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515037-B2 | A molded foam using a copolymer of propylene and an alpha-omega diene having been polymerized in the presence of a metallocene supported catalyst and foaming agent; uniform and fine foamed cells; high foaming magnification; extrusion | CHISSO CORPORATION (JP) | 2003-02-04 | — | — | US | disclosed |
| US-6337372-B1 | ADDITIOIN POLYMERIZATION OF OLEFINS AND PROPYLENE FOR BLOCK POLYMERS | CHISSO CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| US-20010031834-A1 | Using coordination catalyst; flexibility, elasticity; molding materials | CHISSO CORPORATION | 2001-10-18 | — | — | US | disclosed |
| US-20010020045-A1 | Polypropylene base resin composition for foam-molding, foamed article using the same composition, production process for the same foamed article and foam-molded product using the foamed-article | CHISSO CORPORATION | 2001-09-06 | — | — | US | disclosed |