Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | ACACA | Q13085 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | FABP1 | P07148 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7221094 | 0.94 | ACACB (0.42) | ACACBACACAALDH1A1KDM4EMAPT | |
| SCHEMBL7216131 | 0.94 | MAPT (0.36) | ACACBACACAKDM4EMAPTLMNA | |
| SCHEMBL7215993 | 0.91 | KMT2A (0.39) | ACACBACACAALDH1A1KDM4EMAPT | |
| SCHEMBL7216635 | 0.88 | LTA4H (0.39) | ACACBACACATSHRALDH1A1KDM4E | |
| SCHEMBL7216023 | 0.88 | L3MBTL1 (0.34) | TSHRALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL7215817 | 0.87 | NPC1 (0.38) | ALDH1A1KDM4EMAPTLMNARAB9A | |
| SCHEMBL7222381 | 0.87 | GAA (0.33) | KDM4EMAPTLMNAGAAKMT2A | |
| SCHEMBL7975157 | 0.86 | RARB (0.40) | KDM4EMAPTLMNARAB9A | |
| SCHEMBL7215727 | 0.85 | KMT2A (0.44) | ACACBACACAALDH1A1KDM4ELMNA | |
| SCHEMBL7218151 | 0.84 | PPARD (0.34) | TSHRALDH1A1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627651-B1 | Exhibiting preventive and therapeutic effects against HIV infectious diseases wherein R1 is an optionally substituted five- or six-membered ring group; X1 is a free valency or the like; W is a divalent group and inhibitors of HIV (human | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-30 | — | — | US | disclosed |
| EP-1182195-A1 | CYCLIC COMPOUNDS AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |