Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 8/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CCR7 | P32248 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934085 | 0.94 | PLA2G2A (0.39) | ALPLMAPTPLA2G2AKDM4EPOLB | |
| SCHEMBL7968606 | 0.93 | MAPT (0.36) | RARBRARAALPLMAPTCCR5 | |
| SCHEMBL7928473 | 0.92 | ALPL (0.43) | RARBRARAALPLMAPTPLA2G2A | |
| SCHEMBL7249525 | 0.91 | RARB (0.39) | RARBRARACCR5LMNARAB9A | |
| SCHEMBL7216131 | 0.90 | MAPT (0.36) | RARBRARAALPLMAPTKDM4E | |
| SCHEMBL7247416 | 0.90 | RARB (0.46) | RARBRARACCR5KDM4ELMNA | |
| SCHEMBL7922057 | 0.88 | MAPT (0.42) | MAPTCCR5KDM4ERAB9A | |
| SCHEMBL7215817 | 0.88 | NPC1 (0.38) | MAPTKDM4ELMNARAB9A | |
| SCHEMBL7218022 | 0.86 | ACACB (0.38) | MAPTKDM4ELMNARAB9A | |
| SCHEMBL7958575 | 0.85 | RARB (0.53) | RARBRARACCR5CCR7CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |