Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218160 | 0.82 | PDK1 (0.48) | POLBNPSR1TYK2MAPTGAA | |
| SCHEMBL27350224 | 0.82 | ALDH1A1 (0.53) | NPSR1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL2093660 | 0.81 | MEN1 (0.56) | POLBNPSR1TYK2MAPTLMNA | |
| SCHEMBL7218209 | 0.80 | SCN5A (0.47) | NPSR1TYK2GAAKMT2AMEN1 | |
| SCHEMBL27351496 | 0.79 | LCK (0.52) | POLBGAALMNAKMT2AMEN1 | |
| SCHEMBL11402399 | 0.78 | PDK1 (0.59) | POLBGAAKMT2APTGS2CXCL8 | |
| SCHEMBL26088414 | 0.77 | MAPT (0.47) | POLBMAPTLMNAKMT2AMEN1 | |
| SCHEMBL6428445 | 0.73 | ALDH1A1 (0.47) | MAPTGAALMNAKMT2ARAB9A | |
| SCHEMBL26089790 | 0.73 | ALDH1A1 (0.45) | POLBNPSR1TYK2MAPTGAA | |
| SCHEMBL3799518 | 0.72 | MAPT (0.33) | POLBMAPTKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | disclosed |
| US-6410558-B1 | USING INDOLE OR QUINOLINE COMPOUND | MONSANTO TECHNOLOGY LLC | 2002-06-25 | — | — | US | disclosed |
| US-20010046975-A1 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY | 2001-11-29 | — | — | US | disclosed |
| US-6252078-B1 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY | 2001-06-26 | — | — | US | disclosed |
| US-6248894-B1 | SUBSTITUTED PYRROLES | MONSANTO COMPANY | 2001-06-19 | — | — | US | disclosed |
| EP-1088481-A2 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 2001-04-04 | — | — | EP | disclosed |
| US-6166057-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 2000-12-26 | — | — | US | disclosed |
| US-6133252-A | THIOPHENE AND N-BONDED HETEROCYCLIC COMPOUND CHOSEN FROM THE GROUP CONSISTING OF MORPHOLINE, PIPERAZINE, PIPERIDINE, AND PYRROLIDINE, EACH OPTIONALLY SUBSTITUTED WITH C1-C6 ALKYL GROUPS | MONSANTO COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| US-6028101-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 2000-02-22 | — | — | US | disclosed |
| US-RE36562-E | CARBOXAMIDE-SUBSTITUTED THIOPHENES | MONSANTO COMPANY (US) | 2000-02-08 | — | — | US | disclosed |
| US-5998466-A | PREPLANTING | MONSANTO COMPANY (US) | 1999-12-07 | — | — | US | disclosed |
| US-5849723-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5834447-A | THIOPHENE DERIVATIVES | MONSANTO COMPANY (US) | 1998-11-10 | — | — | US | disclosed |
| US-5811411-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5705513-A | HETEROCYCLIC FUNGICIDES WITH PYRIDINE OR FURAN RINGS | MONSANTO COMPANY (US) | 1998-01-06 | — | — | US | disclosed |
| US-5693667-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| US-5498630-A | SUBSTITUTED BENZOTHIOPHENECARBOXAMIDES | MONSANTO COMPANY (US) | 1996-03-12 | — | — | US | disclosed |
| WO-1993007751-A1 | FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO COMPANY (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0538231-A1 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010046975-A1 | Fungicides for the control of take-all disease of plants | CNPY3, NAT1, CBR3 | POLB 3149/4885NPSR1 1139/4885TYK2 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.