SCHEMBL7218291

SCHEMBL7218291

Oc1ccc(-c2ccc(I)c(-c3ccc(O)cc3)c2-c2ccc(O)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.42
ESR2 Q92731 3/20 0.42
MMP3 P08254 2/20 0.40
MMP2 P08253 1/20 0.40
SENP1 Q9P0U3 1/20 0.40
RPS6KA3 P51812 2/20 0.38
HSD17B10 Q99714 1/20 0.38
MGAM O43451 2/20 0.38
GAA P10253 2/20 0.38
SI P14410 2/20 0.38
MGAM2 Q2M2H8 2/20 0.38
ABL1 P00519 1/20 0.38
ABCB1 P08183 1/20 0.38
BCR P11274 1/20 0.38
USP7 Q93009 2/20 0.37
BCL2L1 Q07817 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28958011 0.86 ESR1 (0.56) ESR1ESR2MMP3MMP2SENP1
SCHEMBL13119867 0.77 BCL2L1 (0.64) ESR1ESR2MMP3RPS6KA3HSD17B10
SCHEMBL7714896 0.77 LMNA (0.39) ESR1ESR2HSD17B10BCL2L1
SCHEMBL4351223 0.75 LMNA (0.33) ESR1ESR2HSD17B10BCL2L1
SCHEMBL247903 0.74 SENP1 (0.50) ESR1ESR2MMP3MMP2SENP1
SCHEMBL10000685 0.72 ESR1 (0.40) ESR1ESR2MMP3RPS6KA3HSD17B10
SCHEMBL12801483 0.72 SENP1 (0.43) ESR1ESR2SENP1RPS6KA3HSD17B10
SCHEMBL25386327 0.72 HSD17B1 (0.41) ESR1ESR2SENP1USP7
SCHEMBL6448576 0.72 ABL1 (0.54) ESR1ESR2MMP3MMP2SENP1
SCHEMBL951244 0.72 ABL1 (0.54) ESR1ESR2MMP3MMP2SENP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1272565-A2 FLAME-RETARDANT RESIN MOLDING GENERAL ELECTRIC COMPANY (US) 2003-01-08 EP disclosed
WO-2001072905-A2 FLAME-RETARDANT RESIN MOLDING GENERAL ELECTRIC COMPANY (US) 2001-10-04 WO disclosed