Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216822 | 0.80 | OPRM1 (0.39) | OPRM1 | |
| SCHEMBL7237713 | 0.76 | KIF11 (0.40) | OPRM1KIF11 | |
| SCHEMBL6961426 | 0.72 | SLC6A4 (0.39) | — | |
| SCHEMBL6847573 | 0.70 | OPRM1 (0.37) | OPRM1 | |
| SCHEMBL7244779 | 0.68 | SLC6A4 (0.42) | OPRM1 | |
| Hydrochloric Acid SCHEMBL6195625 | 0.65 | OPRM1 (0.97) | OPRM1 | |
| SCHEMBL6966857 | 0.64 | SIGMAR1 (0.41) | OPRM1 | |
| SCHEMBL6195934 | 0.64 | OPRM1 (0.55) | OPRM1 | |
| SCHEMBL11112455 | 0.63 | OPRM1 (0.41) | OPRM1 | |
| SCHEMBL8040967 | 0.62 | OPRM1 (0.56) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620815-B1 | Selective antagonists for human alpha 1A receptors; benign prostatic hyperplasia, impotency, cardiac arrhythmia treatment; anticholesterol agents; intraocular pressure reduction | SYNAPTIC PHARMACEUTICAL CORPORATION | 2003-09-16 | — | — | US | disclosed |
| US-6159990-A | Oxazolidinones as α1A receptor antagonists | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2000-12-12 | — | — | US | disclosed |