Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2336569 | 0.86 | HDAC4 (0.43) | OPRM1HDAC4 | |
| SCHEMBL30344393 | 0.86 | HDAC4 (0.43) | OPRM1HDAC4 | |
| Hydrochloric Acid SCHEMBL18742513 | 0.84 | CYP3A4 (0.46) | OPRM1HDAC4 | |
| SCHEMBL11971962 | 0.82 | HDAC4 (0.44) | HDAC4 | |
| SCHEMBL5224741 | 0.80 | HDAC4 (0.47) | HDAC4 | |
| Hydrochloric Acid SCHEMBL18742625 | 0.80 | HDAC4 (0.43) | HDAC4 | |
| SCHEMBL23333488 | 0.78 | OPRM1 (0.57) | OPRM1SIGMAR1HTR2CADRB1HDAC4 | |
| SCHEMBL2270935 | 0.77 | SIGMAR1 (0.62) | OPRM1SIGMAR1HTR2CADRB1HDAC4 | |
| SCHEMBL23647453 | 0.77 | ADRB1 (0.40) | OPRM1SIGMAR1HTR2CADRB1HDAC4 | |
| SCHEMBL30017530 | 0.77 | ADRB1 (0.40) | OPRM1SIGMAR1HTR2CADRB1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050248-A1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |