Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.45 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7252964 | 0.96 | RARB (0.40) | RARBRARATSHRKMT2ASMN1; SMN2 | |
| SCHEMBL7958575 | 0.95 | RARB (0.53) | RARBRARATP53TSHR | |
| SCHEMBL7247416 | 0.92 | RARB (0.46) | RARBRARATSHRKDM4E | |
| SCHEMBL7931697 | 0.91 | RXRA (0.41) | PLA2G4BKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL7958827 | 0.91 | RARB (0.42) | RARBRARAKDM4E | |
| SCHEMBL7928473 | 0.89 | ALPL (0.43) | RARBRARAMEN1KMT2ASMPD1 | |
| SCHEMBL7975088 | 0.86 | HDAC1 (0.35) | RARBRARAPTPN11 | |
| SCHEMBL7931034 | 0.85 | MAPT (0.41) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL7934085 | 0.85 | PLA2G2A (0.39) | TSHRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7218340 | 0.85 | LTA4H (0.40) | TP53TSHRKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |