Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217353 | 0.85 | HPGD (0.38) | LMNAALDH1A1L3MBTL1POLBRAB9A | |
| SCHEMBL7218234 | 0.81 | L3MBTL1 (0.46) | LMNAALDH1A1L3MBTL1POLBRAB9A | |
| SCHEMBL7224403 | 0.78 | NLRP3 (0.43) | LMNAALDH1A1L3MBTL1POLBTSHR | |
| SCHEMBL7223579 | 0.76 | NLRP3 (0.56) | LMNAALDH1A1POLBMAPTMAPK1 | |
| SCHEMBL7224806 | 0.75 | ALDH1A1 (0.49) | LMNAALDH1A1RAB9AMAPTTP53 | |
| SCHEMBL7219630 | 0.73 | ALDH1A1 (0.53) | LMNAALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL7219357 | 0.72 | KCNJ11 (0.56) | — | |
| SCHEMBL7223730 | 0.72 | ALOX15 (0.52) | LMNAALDH1A1L3MBTL1POLBTSHR | |
| SCHEMBL7223759 | 0.72 | ALDH1A1 (0.49) | LMNAALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL7225304 | 0.71 | KMT2A (0.47) | ALDH1A1RAB9AHPGDNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |