SCHEMBL721896

SCHEMBL721896

C=CC(=O)OCCOc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.61
DRD2 P14416 1/20 0.54
DRD1 P21728 1/20 0.54
DRD3 P35462 1/20 0.54
ALDH1A1 P00352 5/20 0.49
KMT2A Q03164 2/20 0.49
PTK2B Q14289 1/20 0.49
KDM4E B2RXH2 2/20 0.47
ABCB1 P08183 7/20 0.46
LMNA P02545 2/20 0.45
MAPT P10636 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ELANE P08246 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MEN1 O00255 1/20 0.43
TP53 P04637 2/20 0.42
TSHR P16473 2/20 0.42
HIF1A Q16665 2/20 0.42
HSD17B10 Q99714 1/20 0.42
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29833518 1.00 THRB (0.61) THRBDRD2DRD1DRD3ALDH1A1
SCHEMBL21550262 0.96 THRB (0.57) THRBDRD2DRD1DRD3ALDH1A1
SCHEMBL31304676 0.93 THRB (0.57) THRBDRD2DRD1DRD3ALDH1A1
SCHEMBL15511904 0.93 DRD2 (0.53) THRBDRD2DRD1DRD3ALDH1A1
SCHEMBL29749064 0.93 DRD2 (0.53) THRBDRD2DRD1DRD3ALDH1A1
SCHEMBL29748933 0.92 DRD2 (0.52) THRBDRD2DRD1DRD3ALDH1A1
SCHEMBL317182 0.91 THRB (0.55) THRBDRD2DRD1DRD3ALDH1A1
SCHEMBL30876777 0.91 THRB (0.55) THRBDRD2DRD1DRD3ALDH1A1
SCHEMBL29481429 0.89 THRB (0.52) THRBDRD2DRD1DRD3ALDH1A1
SCHEMBL28878154 0.89 THRB (0.52) THRBDRD2DRD1DRD3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353265-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-11-20 US claimed
US-12391014-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2025-08-19 US claimed
EP-4532187-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-04-09 EP claimed
CN-119144253-A UV (ultraviolet) viscosity reducing glue and preparation method of UV viscosity reducing adhesive tape 浙江耀阳新材料科技有限公司 2024-12-17 CN claimed
WO-2024162057-A1 COMPOSITION デンカ株式会社 2024-08-08 WO claimed
US-20230382065-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-30 US claimed
WO-2023228106-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-30 WO claimed
CN-113527033-B Method for preparing dichlorooctafluorobutane by photochlorination method 浙江巨化股份有限公司氟聚厂 2023-07-25 CN claimed
CN-115873542-B High-stripping-force UV (ultraviolet) curing pressure-sensitive adhesive with excellent reworkability and preparation method thereof 宁波力合博汇光敏材料有限公司 2023-07-21 CN claimed
CN-115873542-A High-peeling-force UV (ultraviolet) curing pressure-sensitive adhesive with excellent reworking property and preparation method thereof 宁波力合博汇光敏材料有限公司 2023-03-31 CN claimed
CN-113527033-A Photochlorination method preparation method of dichlorooctafluorobutane 浙江巨化股份有限公司氟聚厂 2021-10-22 CN claimed
CN-108291109-B Coating composition 巴斯夫欧洲公司 2021-07-09 CN claimed
CN-104797671-B Height adhesion promoting acrylate contact adhesive 3M创新有限公司 2018-03-27 CN claimed
EP-0211067-B1 OXYGEN-PERMEABLE LENSES Bausch & Lomb Incorporated (US) 1991-03-13 EP claimed
US-12630748-B2 Pressure-sensitive adhesive XINMEI FONTANA HOLDING (HONG KONG) LIMITED (CN) 2026-05-19 US disclosed
US-12582752-B2 Medical device and method for manufacturing same TERUMO KABUSHIKI KAISHA (JP) 2026-03-24 US disclosed
EP-4074794-B1 PRESSURE-SENSITIVE ADHESIVE LAYER XINMEI FONTANA HOLDING HONG KONG LTD (CN) 2026-01-28 EP disclosed
US-4037112-A Apparatus for crosslinking ultraviolet light curable coatings PPG INDUSTRIES, INC. (US) 1977-07-19 US disclosed
US-4024296-A Photocatalyst system and pigmented actinic light polymerizable coating compositions containing the same PPG INDUSTRIES, INC. (US) 1977-05-17 US disclosed
US-4017652-A Photocatalyst system and ultraviolet light curable coating compositions containing the same PPG INDUSTRIES, INC. (US) 1977-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12582752-B2 Medical device and method for manufacturing same STS, DEGS1, HPSE THRB 341/4885DRD2 757/4885DRD1 922/4885
US-12630748-B2 Pressure-sensitive adhesive CUTA, PIEZO1, PTK2 THRB 4311/4885DRD2 3018/4885DRD1 2609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.