Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 6/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | SREBF2 | Q12772 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4963448 | 0.89 | MBOAT4 (0.40) | KDM4ELMNACYP3A4TSHRCTSK | |
| SCHEMBL17843154 | 0.85 | CCNC (0.41) | KDM4ELMNACYP3A4TSHRCTSK | |
| SCHEMBL3242600 | 0.85 | CYP1A2 (0.44) | CTSKCTSSMBOAT4CCNCCDK8 | |
| SCHEMBL3870198 | 0.81 | CCNC (0.40) | KDM4ELMNACYP3A4TSHRMBOAT4 | |
| SCHEMBL3869976 | 0.81 | CCNC (0.40) | LMNAMBOAT4CYP19A1CCNCCDK8 | |
| SCHEMBL22637777 | 0.81 | MBOAT4 (0.39) | MBOAT4CYP19A1CCNCCDK8 | |
| SCHEMBL6644862 | 0.78 | MBOAT4 (0.40) | LMNAMBOAT4MEN1KMT2AHRH4 | |
| SCHEMBL25087065 | 0.78 | LOXL2 (0.46) | LMNACYP3A4TSHRMBOAT4CCNC | |
| SCHEMBL13738243 | 0.77 | CCNC (0.37) | KDM4ELMNACYP3A4TSHRMBOAT4 | |
| SCHEMBL22637846 | 0.77 | MBOAT4 (0.44) | KDM4EMBOAT4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119100978-A | Method for preparing 2-propylthioisonicotinamide intermediate through continuous pipeline | 苏州开元民生科技股份有限公司 | 2024-12-10 | — | — | CN | claimed |
| CN-115629139-B | Method for determining impurity content in isonicotinamide by utilizing HPLC | 江苏慈星药业有限公司 | 2024-08-02 | — | — | CN | claimed |
| CN-117185998-B | Preparation method of 2-propylthioisonicotinamide | 苏州开元民生科技股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-117185998-A | Preparation method of 2-propylthioisonicotinamide | 苏州开元民生科技股份有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-115629139-A | Method for determining content of impurities in propylthioisoniazid by using HPLC (high performance liquid chromatography) | 江苏慈星药业有限公司 | 2023-01-20 | — | — | CN | claimed |
| CN-114105869-B | Preparation method of 2-propyl-4-cyanopyridine | 苏州开元民生科技股份有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-114105869-A | Preparation method of 2-propyl-4-cyanopyridine | 苏州开元民生科技股份有限公司 | 2022-03-01 | — | — | CN | claimed |
| EP-4121423-B1 | TETRAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2026-04-29 | — | — | EP | disclosed |
| EP-4121429-B1 | CONDENSED PYRIDINE DERIVATIVES SUBSTITUED BY AMIDE FUNCTIONS AS ACSS2 INHIBITORS | MERCK PATENT GMBH (DE) | 2025-08-13 | — | — | EP | disclosed |
| CN-115335371-B | Tetrazole derivatives | 默克专利股份公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-119100978-A | Method for preparing 2-propylthioisonicotinamide intermediate through continuous pipeline | 苏州开元民生科技股份有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-119100978-A | Method for preparing 2-propylthioisonicotinamide intermediate through continuous pipeline | 苏州开元民生科技股份有限公司 | 2024-12-10 | — | — | CN | disclosed |
| US-20240382468-A2 | TETRAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2024-11-21 | — | — | US | disclosed |
| CN-114105869-A | Preparation method of 2-propyl-4-cyanopyridine | 苏州开元民生科技股份有限公司 | 2022-03-01 | — | — | CN | disclosed |
| WO-2021185789-A1 | CONDENSED PYRIDINE DERIVASTIVES SUBSTITUED BY AMIDE FUNCTIONS AS ACSS2 INHIBITORS | MERCK PATENT GMBH (DE) | 2021-09-23 | — | — | WO | disclosed |
| WO-2021185793-A1 | TETRAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-09-23 | — | — | WO | disclosed |
| EP-2922841-B1 | ALKYL-AMIDE-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES | BRISTOL MYERS SQUIBB CO (US) | 2017-06-07 | — | — | EP | disclosed |
| WO-2012122077-A1 | PRIMARY AMINE DIAZENIUMDIOLATE HETEROCYCLIC DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-09-13 | — | — | WO | disclosed |
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240382468-A2 | TETRAZOLE DERIVATIVES | VHL, BRCA1, POT1 | KDM4E 4514/4885LMNA 2616/4885CYP3A4 2279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.