Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.33 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214177 | 0.79 | CA2 (0.41) | SMN1; SMN2ALDH1A1HSD11B1 | |
| SCHEMBL11040615 | 0.64 | CA2 (0.58) | SMN1; SMN2PBRM1ALDH1A1KMT2ATSHR | |
| SCHEMBL10448603 | 0.63 | TP53 (0.42) | SMN1; SMN2PBRM1ALDH1A1KMT2ATSHR | |
| SCHEMBL8142165 | 0.59 | TSHR (0.52) | SMN1; SMN2ALOX15PBRM1ALDH1A1KMT2A | |
| SCHEMBL15082804 | 0.58 | HTT (0.36) | SMN1; SMN2ALOX15ALDH1A1KMT2ATSHR | |
| SCHEMBL20780483 | 0.58 | HTR6 (0.49) | SMN1; SMN2ALDH1A1POLBTP53RECQL | |
| SCHEMBL10242244 | 0.57 | SLC6A3 (0.46) | SMN1; SMN2ALDH1A1KMT2ATSHRTP53 | |
| SCHEMBL10731027 | 0.57 | MAPT (0.53) | SMN1; SMN2ALDH1A1KMT2APOLBTP53 | |
| SCHEMBL16064832 | 0.57 | SLC6A3 (0.46) | SMN1; SMN2ALDH1A1KMT2ATSHRTP53 | |
| SCHEMBL8852665 | 0.57 | GAA (0.39) | SMN1; SMN2ALDH1A1KMT2ATSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6504046-B1 | Cyclization of nitriles using acids, to form oxazolinone chemical intermediates such as 2-phenyl-4-isopropyl-4-methyl-1,3-oxazol-5-one, used as fungicides | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-07 | — | — | US | disclosed |