Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.55 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.45 |
| ▸ | STAMBP | O95630 | 1/20 | 0.45 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314248 | 0.86 | HPGDS (0.51) | HPGDSSIRT3F7F3SARM1 | |
| Isoquinoline SCHEMBL28230213 | 0.85 | MGAM (0.56) | HPGDSSIRT3F7F3SARM1 | |
| SCHEMBL3788261 | 0.84 | MGAM (0.64) | HPGDSPSMD14LRRK2MGAMKDM4E | |
| SCHEMBL4900459 | 0.82 | HPGDS (0.55) | HPGDSLRRK2MGAMKDM4ESMN1; SMN2 | |
| SCHEMBL28946126 | 0.79 | ALOX15 (0.54) | HPGDSPSMD14KDM4EHTTALDH1A1 | |
| SCHEMBL29362497 | 0.79 | MGAM (0.71) | HPGDSPSMD14STAMBPCOPS5MAP4K4 | |
| SCHEMBL23372 | 0.79 | MGAM (0.71) | HPGDSPSMD14STAMBPCOPS5MAP4K4 | |
| SCHEMBL35212113 | 0.77 | HPGDS (0.44) | HPGDSLRRK2MAP4K4DYRK1AMGAM | |
| Hydrochloric Acid SCHEMBL5311903 | 0.77 | MGAM (0.69) | HPGDSPSMD14STAMBPCOPS5MAP4K4 | |
| Hydrochloric Acid SCHEMBL28841803 | 0.77 | MGAM (0.69) | HPGDSPSMD14STAMBPCOPS5MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124198-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | GILEAD SCIENCES INC (US) | 2026-05-07 | — | — | US | claimed |
| US-20260124198-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | GILEAD SCIENCES INC (US) | 2026-05-07 | — | — | US | disclosed |
| EP-3976608-A1 | THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | Ideaya Biosciences, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |
| CN-107151240-A | Polysubstituted carbostyril compound of one class and its production and use | 中国科学院上海药物研究所 | 2017-09-12 | — | — | CN | disclosed |
| US-20120053201-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260124198-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | ZC3HAV1, CCR1, CCR6 | HPGDS 3568/4885SIRT3 3204/4885F7 432/4885 |
| US-20120053201-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | HDAC6, HDAC1, HDAC2 | HPGDS 528/4885SIRT3 108/4885F7 2094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.