Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476384 | 0.81 | HSD11B1 (0.33) | MAPTALDH1A1CYP3A4HSD11B1KDM4E | |
| SCHEMBL4954512 | 0.69 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL7330891 | 0.68 | KCNJ1 (0.37) | MAPTMEN1KMT2A | |
| SCHEMBL10875879 | 0.67 | HSD11B1 (0.39) | MEN1KMT2AALDH1A1CYP3A4HSD11B1 | |
| SCHEMBL7565613 | 0.66 | — | — | |
| SCHEMBL28381016 | 0.65 | CPA1 (0.33) | MAPTALDH1A1HSD11B1SMN1; SMN2KDM4E | |
| SCHEMBL4367842 | 0.64 | PDE1C (0.34) | MEN1KMT2ATSHR | |
| SCHEMBL7323975 | 0.63 | ALDH1A1 (0.36) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL23748559 | 0.63 | NPC1 (0.33) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL20746417 | 0.62 | FBP1 (0.36) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596734-B1 | Method for stimulating, regulating and modulating metabolism of fats in adipose tissue in mammals, comprising administering to a mammal an effective amount of a beta 3- adrenoreceptor agonist | MOLECULAR DESIGN INTERNATIONAL, INC. | 2003-07-22 | — | — | US | disclosed |