Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 2/20 | 0.49 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27986576 | 0.83 | HTR1A (0.50) | MEN1KMT2ALMNAPOLBMAPT | |
| Methoxymethane SCHEMBL27521593 | 0.81 | HTR1A (0.46) | MEN1KMT2ALMNAHTTPOLB | |
| SCHEMBL10652958 | 0.79 | CES2 (0.53) | HPGDMEN1KMT2ALMNAHTT | |
| SCHEMBL1601620 | 0.79 | ALDH1A1 (0.53) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL9511525 | 0.79 | VCAM1 (0.56) | HPGDMEN1KMT2ALMNAHTT | |
| SCHEMBL29936572 | 0.79 | VCAM1 (0.56) | HPGDMEN1KMT2ALMNAHTT | |
| SCHEMBL1601110 | 0.79 | IDH1 (0.58) | L3MBTL1HPGDMEN1KMT2ALMNA | |
| SCHEMBL27856352 | 0.78 | ALDH1A1 (0.56) | L3MBTL1HPGDLMNAHTTNPC1 | |
| SCHEMBL16233087 | 0.78 | SMN1; SMN2 (0.61) | TTRMEN1KMT2ALMNAHTT | |
| SCHEMBL6157822 | 0.77 | TTR (0.56) | HSPB1TTRHPSEHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596734-B1 | Method for stimulating, regulating and modulating metabolism of fats in adipose tissue in mammals, comprising administering to a mammal an effective amount of a beta 3- adrenoreceptor agonist | MOLECULAR DESIGN INTERNATIONAL, INC. | 2003-07-22 | — | — | US | disclosed |