Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661089 | 0.89 | ALDH1A1 (0.51) | ALDH1A1THRBSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL11057029 | 0.87 | GPR174 (0.55) | ALDH1A1SMN1; SMN2HTTL3MBTL1KMT2A | |
| SCHEMBL7219373 | 0.84 | ALDH1A1 (0.48) | ALDH1A1THRBSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL10407939 | 0.81 | HTT (0.50) | ALDH1A1SMN1; SMN2HTTL3MBTL1GPR174 | |
| SCHEMBL1065069 | 0.81 | GPR174 (0.61) | ALDH1A1SMN1; SMN2HTTL3MBTL1KMT2A | |
| SCHEMBL7219072 | 0.81 | GAA (0.51) | ALDH1A1THRBSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL7219385 | 0.79 | ELANE (0.66) | ALDH1A1THRBSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL7786879 | 0.79 | ACACB (0.44) | ALDH1A1THRBKMT2AGPR174TRPM8 | |
| SCHEMBL9861628 | 0.79 | PLK1 (0.64) | ALDH1A1THRBL3MBTL1KMT2ATHRA | |
| SCHEMBL10014123 | 0.78 | RAB9A (0.58) | ALDH1A1THRBSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624236-B1 | Sol-gel-condensable cyclosiloxane(meth) acrylates; dentistry | 3M ESPE AG (DE) | 2003-09-23 | — | — | US | disclosed |