Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 8/20 | 0.40 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661089 | 0.89 | ALDH1A1 (0.51) | ALDH1A1THRBTRPM8GPR174KMT2A | |
| SCHEMBL7219373 | 0.84 | ALDH1A1 (0.48) | ALDH1A1THRBTRPM8GPR174KMT2A | |
| SCHEMBL7219384 | 0.79 | ALDH1A1 (0.50) | ALDH1A1THRBTRPM8GPR174KMT2A | |
| SCHEMBL7219072 | 0.78 | GAA (0.51) | ALDH1A1THRBTRPM8PSMB5GPR174 | |
| SCHEMBL12035988 | 0.77 | RAB9A (0.51) | ALDH1A1TRPM8TSHRGPR174KMT2A | |
| SCHEMBL7219064 | 0.77 | THRB (0.52) | ACACBACACAALDH1A1THRBKMT2A | |
| SCHEMBL9621041 | 0.77 | LPL (0.46) | ACACBACACAALDH1A1THRBKMT2A | |
| SCHEMBL2106821 | 0.76 | ALDH1A1 (0.66) | ALDH1A1TSHRGPR174KMT2A | |
| SCHEMBL12035980 | 0.76 | RAB9A (0.49) | ALDH1A1TRPM8GPR174KMT2A | |
| SCHEMBL15869197 | 0.76 | GPR174 (0.49) | ALDH1A1TSHRGPR174KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141094-A1 | CYCLOSILOXANE-BASED CROSS-LINKABLE MONOMERS, PRODUCTION THEREOF AND USE THEREOF IN POLYMERISABLE MATERIALS | 3M Espe AG (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000042092-A1 | CYCLOSILOXANE-BASED CROSS-LINKABLE MONOMERS, PRODUCTION THEREOF AND USE THEREOF IN POLYMERISABLE MATERIALS | 3M ESPE AG (DE) | 2000-07-20 | — | — | WO | disclosed |