Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219729 | 0.86 | L3MBTL1 (0.42) | HPGDALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL21705945 | 0.78 | GAA (0.36) | HPGDALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL7215762 | 0.78 | L3MBTL1 (0.37) | HPGDALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL12841907 | 0.74 | LOXL2 (0.39) | HPGDALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL12841855 | 0.74 | CYP11B1 (0.39) | HPGDALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL13069414 | 0.73 | MAPK1 (0.35) | HPGDALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL12841908 | 0.72 | NOS3 (0.33) | HPGDALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL12842021 | 0.70 | AR (0.37) | HPGDALDH1A1KDM4EL3MBTL1AR | |
| SCHEMBL12841667 | 0.70 | HRH4 (0.37) | HPGDALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL10731748 | 0.70 | HSD17B10 (0.40) | HPGDALDH1A1KDM4EL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |