Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219383 | 0.92 | — | — | |
| SCHEMBL7225877 | 0.90 | — | — | |
| SCHEMBL7226518 | 0.85 | KDM4E (0.31) | KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7221841 | 0.74 | CRHR1 (0.32) | — | |
| SCHEMBL7220502 | 0.73 | CRHR1 (0.32) | KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7227988 | 0.62 | CRHR1 (0.35) | — | |
| SCHEMBL7227320 | 0.59 | CRHR1 (0.44) | — | |
| SCHEMBL7219519 | 0.59 | CRHR1 (0.37) | KDM4ESMN1; SMN2 | |
| SCHEMBL7219475 | 0.52 | CRHR1 (0.44) | — | |
| SCHEMBL29127366 | 0.51 | ALDH1A1 (0.40) | KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103553-A2 | Substituted heterocyclic derivatives | Pfizer Products Inc. (US) | 2001-05-30 | — | — | EP | claimed |
| US-6525067-B1 | Corticotropin releasing factor antagonists; such as 1-(2-methyl-8-(2,4,6-trimethyl-phenyl)-quinolin-4-yl)-propan-1-one-oxime | PFIZER INC | 2003-02-25 | — | — | US | disclosed |
| EP-1103553-A2 | Substituted heterocyclic derivatives | Pfizer Products Inc. (US) | 2001-05-30 | — | — | EP | disclosed |