SCHEMBL722025

SCHEMBL722025

CC(C)(C)COC(=O)CC(=O)OCC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.50
MGAM O43451 2/20 0.50
SI P14410 2/20 0.50
MGAM2 Q2M2H8 2/20 0.50
KMT2A Q03164 1/20 0.38
CYP2C19 P33261 1/20 0.36
TSHR P16473 3/20 0.35
MIF P14174 1/20 0.33
HSD17B10 Q99714 2/20 0.32
LMNA P02545 1/20 0.32
TET2 Q6N021 1/20 0.31
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1247793 0.87 MGAM (0.39) GAAMGAMSIMGAM2KMT2A
SCHEMBL2059154 0.87 MGAM (0.50) GAAMGAMSIMGAM2KMT2A
SCHEMBL2485813 0.83 ADRA2A (0.42) GAAMGAMSIMGAM2KMT2A
SCHEMBL12028701 0.81 LMNA (0.35) GAAMGAMSIMGAM2KMT2A
SCHEMBL722286 0.81 NAAA (0.43) GAAMGAMSIMGAM2KMT2A
SCHEMBL2535542 0.81 CYP2C19 (0.35) GAAMGAMSIMGAM2KMT2A
SCHEMBL872954 0.81 CYP2C19 (0.35) GAAMGAMSIMGAM2KMT2A
SCHEMBL17826614 0.80 GAA (0.34) GAAMGAMSIMGAM2KMT2A
SCHEMBL9238728 0.80 TET2 (0.39) GAAMGAMSIMGAM2KMT2A
SCHEMBL6597146 0.80 MGAM (0.33) GAAMGAMSIMGAM2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110177798-B Catalyst and process for preparing same 博里利斯股份公司 2022-08-30 CN disclosed
EP-2876118-B1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFIN, CATALYST FOR USE IN POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO LTD (JP) 2022-04-06 EP disclosed
EP-3689918-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, AND PROPYLENE- -OLEFIN COPOLYMER Toho Titanium CO., LTD. (JP) 2020-08-05 EP disclosed
US-20200199274-A1 CATALYST FOR POLYMERIZATION OF OLEFIN, METHOD FOR PRODUCING CATALYST FOR POLYMERIZATION OF OLEFIN, METHOD FOR PRODUCING POLYMER OF OLEFIN AND PROPYLENE-ALPHA-OLEFIN COPOLYMER TOHO TITANIUM CO., LTD. (JP) 2020-06-25 US disclosed
US-20200140577-A1 CATALYST FOR POLYMERIZATION OF AN OLEFIN, METHOD FOR PRODUCING POLYMER OF OLEFIN AND PROPYLENE-alpha-OLEFIN COPOLYMER TOHO TITANIUM CO., LTD. (JP) 2020-05-07 US disclosed
EP-3623393-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, AND PROPYLENE/ -OLEFIN COPOLYMER Toho Titanium Co., Ltd. (JP) 2020-03-18 EP disclosed
CN-105073757-B Dyeing process using a hair-dyeing precursor obtained from an iridoid, composition, precursor and device comprising such a precursor 莱雅公司 2019-12-17 CN disclosed
US-10364304-B2 Method for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer TOHO TITANIUM CO., LTD. (JP) 2019-07-30 US disclosed
EP-1533322-B1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST TOHO TITANIUM CO LTD (JP) 2019-05-01 EP disclosed
EP-2963065-B1 PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, CATALYST FOR POLYMERIZING OLEFINS, AND PRODUCTION METHOD FOR POLYMERIZED OLEFINS TOHO TITANIUM CO LTD (JP) 2018-04-04 EP disclosed
US-20050250918-A1 Catalyst for olefin polymerization and process for polymerizing olefins TOHO CATALYST CO., LTD. (JP) 2005-11-10 US disclosed
US-20050227856-A1 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2005-10-13 US disclosed
EP-1533322-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST Toho Catalyst Co., Ltd. (JP) 2005-05-25 EP disclosed
US-20050032991-A1 Olefin polymerization catalyst TOHO CATALYST CO, LTD. (JP) 2005-02-10 US disclosed
US-20040234464-A1 Photoprotective cosmetic compositions comprising para-aminobenzalmalonate-substituted s-triazine compounds L'OREAL (FR) 2004-11-25 US disclosed
WO-2004067539-A1 PHOTOPROTECTIVE COMPOSITIONS BASED ON METHYLTRIALKYLSILANES CONTAINING A CINNAMATE, CINNAMAMIDE, BENZALMALONAMIDE OR BENZALMALONATE FUNCTION L'OREAL (FR) 2004-08-12 WO disclosed
EP-0993442-B1 HYDRAZINE DERIVATIVES HOFFMANN LA ROCHE (CH) 2003-04-23 EP disclosed
US-6235787-B1 ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES; BONE DISORDERS; SKIN DISORDERS; MULTIPLE SCLEROSIS HOFFMANN-LA ROCHE INC. 2001-05-22 US disclosed
EP-0993442-A1 HYDRAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2000-04-19 EP disclosed
WO-1999001428-A1 HYDRAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1999-01-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040234464-A1 Photoprotective cosmetic compositions comprising para-aminobenzalmalonate-substituted s-triazine compounds TYR, MSH6, ERCC5 GAA 1571/4885MGAM 3536/4885SI 485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.