SCHEMBL7220719

SCHEMBL7220719

CO[C]1C=CC=C(OC)C1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2456326 0.81 TSHR (0.31) MAPT
SCHEMBL2245503 0.76
SCHEMBL5640318 0.74
SCHEMBL5644679 0.74
SCHEMBL6138233 0.70
SCHEMBL7623161 0.70
SCHEMBL1049806 0.64
SCHEMBL7638199 0.62
SCHEMBL1049678 0.60
SCHEMBL9320067 0.60 BRD4 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192701-A1 BICYCLIC KINASE INHIBITORS AND USES THEREOF IOMX THERAPEUTICS AG (DE) 2023-06-22 US claimed
EP-4143191-A2 BICYCLIC KINASE INHIBITORS AND USES THEREOF iOmx Therapeutics AG (DE) 2023-03-08 EP claimed
WO-2021219731-A2 BICYCLIC KINASE INHIBITORS AND USES THEREOF IOMX THERAPEUTICS AG (DE) 2021-11-04 WO claimed
CN-111393359-A Pyridine salt-containing N- (cinnamoyl) -N' - (substituted) propyl hydrazide compound and preparation method and application thereof 贵州大学 2020-07-10 CN claimed
EP-2920189-B1 PROCESS FOR MAKING NOVEL CHIRAL PHOSPHORUS LIGANDS BOEHRINGER INGELHEIM INT (DE) 2017-08-02 EP claimed
EP-2920189-A1 PROCESS FOR MAKING NOVEL CHIRAL PHOSPHORUS LIGANDS Boehringer Ingelheim International GmbH (DE) 2015-09-23 EP claimed
US-8816112-B2 Process for making novel chiral phosphorus ligands BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-08-26 US claimed
WO-2014078491-A1 PROCESS FOR MAKING NOVEL CHIRAL PHOSPHORUS LIGANDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-05-22 WO claimed
US-20140135506-A1 PROCESS FOR MAKING NOVEL CHIRAL PHOSPHORUS LIGANDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-05-15 US claimed
CN-1112118-A Epi-epibatidine derivatives EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1995-11-22 CN claimed
EP-0657455-A1 Epi-epibatidine derivatives, a process and intermediates for preparing them and epi-epibatidine and medicaments containing the epi-epibatidine derivatives and/or epi-epibatidine and the use of them EGIS GYOGYSZERGYAR (HU) 1995-06-14 EP claimed
EP-3318555-B1 BIFUNCTIONAL CHELATING AGENTS BWXT MEDICAL LTD (CA) 2023-08-16 EP disclosed
US-20230192701-A1 BICYCLIC KINASE INHIBITORS AND USES THEREOF IOMX THERAPEUTICS AG (DE) 2023-06-22 US disclosed
EP-4143191-A2 BICYCLIC KINASE INHIBITORS AND USES THEREOF iOmx Therapeutics AG (DE) 2023-03-08 EP disclosed
WO-2021219731-A2 BICYCLIC KINASE INHIBITORS AND USES THEREOF IOMX THERAPEUTICS AG (DE) 2021-11-04 WO disclosed
CN-1112118-A Epi-epibatidine derivatives EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1995-11-22 CN disclosed
EP-0657455-A1 Epi-epibatidine derivatives, a process and intermediates for preparing them and epi-epibatidine and medicaments containing the epi-epibatidine derivatives and/or epi-epibatidine and the use of them EGIS GYOGYSZERGYAR (HU) 1995-06-14 EP disclosed
EP-0072013-B1 PYRROLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS MERCK & CO. INC. (US) 1986-04-16 EP disclosed
US-4434175-A 5-AROYL-PYRROLE ALKANOIC ACIDS MERCK & CO., INC. (US) 1984-02-28 US disclosed
EP-0072013-A1 Pyrrole compounds as anti-inflammatory and analgesic agents MERCK & CO. INC. (US) 1983-02-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140135506-A1 PROCESS FOR MAKING NOVEL CHIRAL PHOSPHORUS LIGANDS PHOSPHO1, INPP5B, PLCG2 CYP3A4 2608/4885MAPT 4123/4885
US-20230192701-A1 BICYCLIC KINASE INHIBITORS AND USES THEREOF MITF, PRKDC, PRKACA CYP3A4 4220/4885MAPT 1803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.