SCHEMBL9320067

SCHEMBL9320067

COC1=CC=CN(C)C(=O)C1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.42
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9319715 0.68 BRD4 (0.32) BRD4
SCHEMBL17816405 0.67
SCHEMBL9319064 0.66 NPC1 (0.35) BRD4SMN1; SMN2
SCHEMBL6138233 0.63
SCHEMBL35261 0.61
SCHEMBL3369576 0.61
SCHEMBL17472738 0.61
SCHEMBL27685180 0.61
SCHEMBL7220719 0.60 CYP3A4 (0.32)
SCHEMBL9354170 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES Ananda Scientific, Inc. (US) 2025-06-19 US disclosed
EP-0267277-B1 COMPOSITIONS COMPRISING 1-SUBSTITUTED LACTAMS WHITBY RESEARCH INC (US) 1994-01-19 EP disclosed
EP-0325613-B1 PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC AGENTS WHITBY RESEARCH, Inc. (US) 1993-09-08 EP disclosed
US-5142044-A Lactam derivatives WHITBY RESEARCH, INC. (US) 1992-08-25 US disclosed
EP-0267277-A4 COMPOSITIONS COMPRISING 1-SUBSTITUTED LACTAMS. NELSON RES & DEV COMPANY (US) 1990-03-21 EP disclosed
US-4801586-A N-HETEROCYCLES NELSON RESEARCH & DEVELOPMENT CO. (US) 1989-01-31 US disclosed
US-4755535-A Compositions comprising 1-substituted azacycloalkenes NELSON RESEARCH & DEVELOPMENT CO. (US) 1988-07-05 US disclosed
EP-0267277-A1 COMPOSITIONS COMPRISING 1-SUBSTITUTED LACTAMS. NELSON RES & DEV (US) 1988-05-18 EP disclosed
WO-1987006583-A1 COMPOSITIONS COMPRISING 1-SUBSTITUTED LACTAMS NELSON RESEARCH AND DEVELOPMENT COMPANY (US) 1987-11-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES CNR2, CNR1, FAAH BRD4 1767/4885GAA 2993/4885SMN1; SMN2 2064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.