Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2282860 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1RAB9ATSHRL3MBTL1 | |
| SCHEMBL7221090 | 0.82 | L3MBTL1 (0.48) | KDM4ERAB9ATSHRL3MBTL1GAA | |
| SCHEMBL2278855 | 0.81 | L3MBTL1 (0.47) | KDM4EALDH1A1RAB9ATSHRL3MBTL1 | |
| SCHEMBL7214195 | 0.76 | ALDH1A1 (0.42) | KDM4EALDH1A1RAB9ATSHRL3MBTL1 | |
| SCHEMBL7220252 | 0.75 | RAB9A (0.46) | KDM4EALDH1A1RAB9ATSHRL3MBTL1 | |
| SCHEMBL2284503 | 0.75 | KMT2A (0.50) | KDM4EALDH1A1RAB9ATSHRL3MBTL1 | |
| SCHEMBL2279647 | 0.74 | L3MBTL1 (0.46) | KDM4EALDH1A1RAB9ATSHRL3MBTL1 | |
| SCHEMBL7220336 | 0.73 | POLB (0.62) | KDM4EALDH1A1RAB9ATSHRL3MBTL1 | |
| SCHEMBL2279827 | 0.71 | SMN1; SMN2 (0.59) | KDM4EALDH1A1RAB9ATSHRL3MBTL1 | |
| SCHEMBL11277993 | 0.71 | ALDH1A1 (0.52) | KDM4EALDH1A1RAB9ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610692-B1 | Anticoagulants | MERCK & CO., INC. | 2003-08-26 | — | — | US | disclosed |