Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 3/20 | 0.60 |
| ▸ | CDC25B | P30305 | 3/20 | 0.60 |
| ▸ | CDC25C | P30307 | 3/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.60 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | EIF4E | P06730 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215657 | 0.91 | CDC25A (0.60) | CDC25ACDC25BCDC25CDUSP3SREBF2 | |
| SCHEMBL7217226 | 0.89 | CDC25A (0.62) | CDC25ACDC25BCDC25CDUSP3SREBF2 | |
| SCHEMBL7214904 | 0.88 | L3MBTL1 (0.61) | SREBF2MAPTL3MBTL1EIF4EMEN1 | |
| SCHEMBL7221010 | 0.87 | L3MBTL1 (0.54) | CDC25ACDC25BCDC25CDUSP3SREBF2 | |
| SCHEMBL16180612 | 0.86 | SMN1; SMN2 (0.59) | SREBF2MAPTTP53L3MBTL1POLB | |
| SCHEMBL1505172 | 0.86 | L3MBTL1 (0.54) | CDC25ACDC25BCDC25CDUSP3SREBF2 | |
| SCHEMBL7215066 | 0.86 | L3MBTL1 (0.52) | SREBF2MAPTL3MBTL1MEN1NPC1 | |
| SCHEMBL23742625 | 0.84 | TRPM8 (0.57) | MAPTL3MBTL1EIF4EMEN1KMT2A | |
| SCHEMBL23742629 | 0.84 | KDM4E (0.52) | CDC25ACDC25BCDC25CDUSP3MAPT | |
| SCHEMBL10655855 | 0.81 | CDC25A (0.48) | CDC25ACDC25BCDC25CDUSP3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6545009-B1 | Imidazole, oxazole and thiazole derivatives for regulation of peroxisome proliferator-activated receptor function; improving insulin resistance, treating impaired glucose tolerance and obesity, enhancing insulin sensitivity, etc. | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-04-08 | — | — | US | disclosed |
| CN-1314899-A | Retinoid-associated receptor regulators | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-09-26 | — | — | CN | disclosed |
| EP-1092711-A1 | RETINOID-ASSOCIATED RECEPTOR REGULATORS | Takeda Chemical Industries, Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |