Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 4/20 | 0.60 |
| ▸ | CDC25B | P30305 | 4/20 | 0.60 |
| ▸ | CDC25C | P30307 | 4/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 4/20 | 0.60 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | EIF4E | P06730 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220970 | 0.91 | CDC25A (0.60) | CDC25ACDC25BCDC25CDUSP3SREBF2 | |
| SCHEMBL7217226 | 0.89 | CDC25A (0.62) | CDC25ACDC25BCDC25CDUSP3SREBF2 | |
| SCHEMBL7217144 | 0.89 | KDM4E (0.62) | CDC25ACDC25BCDC25CDUSP3SREBF2 | |
| SCHEMBL7217145 | 0.81 | KDM4E (0.59) | CDC25ACDC25BCDC25CDUSP3MAPT | |
| SCHEMBL7220984 | 0.81 | RAB9A (0.55) | MAPTEIF4EKMT2ANPC1RAB9A | |
| SCHEMBL10661761 | 0.81 | CDC25A (0.48) | CDC25ACDC25BCDC25CDUSP3MAPT | |
| SCHEMBL7215074 | 0.79 | CYP19A1 (0.50) | SREBF2EIF4EKMT2ANPC1RAB9A | |
| SCHEMBL7214904 | 0.79 | L3MBTL1 (0.61) | SREBF2MAPTEIF4EKMT2ANPC1 | |
| SCHEMBL1505401 | 0.79 | SMN1; SMN2 (0.53) | MAPTEIF4ETP53POLBKMT2A | |
| SCHEMBL7221980 | 0.78 | KDM4E (0.75) | CDC25ACDC25BCDC25CDUSP3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6545009-B1 | Imidazole, oxazole and thiazole derivatives for regulation of peroxisome proliferator-activated receptor function; improving insulin resistance, treating impaired glucose tolerance and obesity, enhancing insulin sensitivity, etc. | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-04-08 | — | — | US | disclosed |
| CN-1314899-A | Retinoid-associated receptor regulators | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-09-26 | — | — | CN | disclosed |
| EP-1092711-A1 | RETINOID-ASSOCIATED RECEPTOR REGULATORS | Takeda Chemical Industries, Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |