Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251269 | 0.86 | GABRA1 (0.47) | GABRA1GABRB2ALDH1A1ADRB2ADRB1 | |
| SCHEMBL1081636 | 0.83 | GABRA1 (0.59) | GABRA1GABRB2ALDH1A1LMNAKDM4E | |
| SCHEMBL11168973 | 0.83 | GABRA1 (0.46) | GABRA1GABRB2ALDH1A1CYP1A2KDM4E | |
| SCHEMBL7591364 | 0.82 | GABRA1 (0.44) | GABRA1GABRB2ALDH1A1ADRB2ADRB1 | |
| SCHEMBL3251271 | 0.82 | CYP3A4 (0.47) | GABRA1GABRB2ALDH1A1LMNACYP1A2 | |
| SCHEMBL8607968 | 0.82 | GABRA1 (0.47) | GABRA1GABRB2ALDH1A1ADRB2ADRB1 | |
| SCHEMBL8360631 | 0.81 | GABRA1 (0.43) | GABRA1GABRB2ALDH1A1ADRB2ADRB1 | |
| Ethylene SCHEMBL11742468 | 0.81 | CYP3A4 (0.46) | GABRA1GABRB2ALDH1A1LMNACYP1A2 | |
| SCHEMBL3672603 | 0.81 | MAPT (0.39) | GABRA1GABRB2ALDH1A1LMNAADRA2C | |
| SCHEMBL8520457 | 0.79 | GABRA1 (0.42) | GABRA1GABRB2ALDH1A1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1249181-C | Ink composition | ROHM & HEAS CO (US) | 2006-04-05 | — | — | CN | claimed |
| US-5741830-A | COPOLYMER OF A FLUORINE CONTAINING STYRENE DERIVATIVE AND N,N-DIMETHYL(METH)ACRYLAMIDE | MENICON CO., LTD. (JP) | 1998-04-21 | — | — | US | claimed |
| EP-0269275-B1 | Thermoplastic elastomer composition | MITSUI PETROCHEMICAL IND (JP) | 1994-05-11 | — | — | EP | claimed |
| EP-0266982-B1 | Laminated and molded article prepared therefrom | MITSUI PETROCHEMICAL IND (JP) | 1994-04-27 | — | — | EP | claimed |
| EP-0578087-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-01-12 | — | — | EP | claimed |
| JP-55098175-A | — | — | None | — | — | JP | disclosed |
| JP-7178830-A | — | — | None | — | — | JP | disclosed |
| EP-3995493-B1 | CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE | TOKUYAMA CORP (JP) | 2024-07-03 | — | — | EP | disclosed |
| CN-114051497-B | Chromene compounds and photochromic optical articles | 株式会社德山 | 2024-06-28 | — | — | CN | disclosed |
| CN-113543753-B | Method for absorbing or discharging moisture in ophthalmic medical device and ophthalmic medical device | 国立大学法人东北大学 | 2024-04-19 | — | — | CN | disclosed |
| EP-3936091-B1 | METHOD FOR ABSORBING OR DISCHARGING WATER IN OPHTHALMIC MEDICAL DEVICE AND OPHTHALMIC MEDICAL DEVICE | UNIV TOHOKU (JP) | 2023-07-19 | — | — | EP | disclosed |
| US-20220213050-A1 | CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE | TOKUYAMA CORPORATION (JP) | 2022-07-07 | — | — | US | disclosed |
| EP-0578087-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5229449-A | Sulfonated and esterified; dispersant, mud stabilizer, plasticizer | KAWASAKI STEEL CORPORATION (JP) | 1993-07-20 | — | — | US | disclosed |
| US-5191049-A | Formation of dispersants | KAWASAKI STEEL CORP. (JP) | 1993-03-02 | — | — | US | disclosed |
| US-5166275-A | Indene, styrene and derivatives copolymerizable with maleic anhydride | KAWASAKI STEEL CORPORATION (JP) | 1992-11-24 | — | — | US | disclosed |
| US-4963606-A | CONTAINING BROMINATED CYCLOALIPHATIC FLAME RETARDERS | ETHYL CORPORATION (US) | 1990-10-16 | — | — | US | disclosed |
| US-4476267-A | High impact polystyrene containing halophenoxyalkylsilane flame retardant | ETHYL CORPORATION (US) | 1984-10-09 | — | — | US | disclosed |
| US-4277637-A | TREATMENT WITH SULFONIC ACID ION EXCHANGE RESIN | THE DOW CHEMICAL COMPANY (US) | 1981-07-07 | — | — | US | disclosed |
| JP-S5598175-A | PREPARATION OF LOW-MOLECULAR WEIGHT POLYACID ANHYDRIDE | SUMITOMO CHEM CO LTD | 1980-07-25 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213050-A1 | CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE | CRY1, CRY2, TRIP13 | GABRA1 4077/4885GABRB2 4318/4885ALDH1A1 779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.