Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7231823 | 0.90 | OPRD1 (0.40) | ALDH1A1OPRD1OPRK1KMT2AKDM4E | |
| SCHEMBL7229778 | 0.89 | KMT2A (0.38) | ALDH1A1OPRD1OPRK1KMT2AMEN1 | |
| SCHEMBL7223661 | 0.89 | OPRD1 (0.41) | ALDH1A1OPRD1OPRK1GHSRMBTPS1 | |
| SCHEMBL7222289 | 0.87 | RBP4 (0.41) | ALDH1A1OPRD1OPRK1KMT2AMEN1 | |
| SCHEMBL7231689 | 0.86 | KMT2A (0.42) | ALDH1A1OPRK1KMT2AKDM4EMEN1 | |
| SCHEMBL7230028 | 0.85 | CYP3A4 (0.44) | OPRM1OPRD1OPRK1KMT2AMEN1 | |
| SCHEMBL6782827 | 0.85 | GAA (0.41) | ALDH1A1OPRM1OPRD1GHSRMBTPS1 | |
| Hydrochloric Acid SCHEMBL6785737 | 0.84 | GAA (0.40) | ALDH1A1OPRM1OPRD1GHSRMBTPS1 | |
| SCHEMBL7223175 | 0.84 | OPRD1 (0.46) | OPRM1OPRD1OPRK1MBTPS1KMT2A | |
| SCHEMBL7221710 | 0.83 | KCNH2 (0.42) | MBTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642257-B2 | Fewer side-effects than do the conventional analgesics; 4-hydroxypiperidine derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| US-20020049229-A1 | Agents for treating neuropathic pain | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-25 | — | — | US | disclosed |
| EP-1182193-A1 | REMEDIES FOR NEUROPATHIC PAIN | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049229-A1 | Agents for treating neuropathic pain | OPRM1, OPRK1, OPRL1 | ALDH1A1 310/4885MAPK1 1574/4885OPRM1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.