Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.59 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 10/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 10/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8208 | 0.86 | KDM4E (0.64) | GABRA1GABRA5GABRB2KDM4ENPC1 | |
| SCHEMBL1691920 | 0.85 | KDM4E (0.63) | GABRA1GABRA5GABRB2KDM4ENPC1 | |
| SCHEMBL7222041 | 0.80 | SLC2A2 (0.63) | GABRA1GABRA5GABRB2KDM4ENPC1 | |
| SCHEMBL1691661 | 0.79 | KDM4E (0.69) | GABRA1GABRA5GABRB2KDM4ENPC1 | |
| SCHEMBL10999904 | 0.78 | GABRA2 (0.60) | GABRB2KDM4EHTTSLC2A1 | |
| SCHEMBL1431027 | 0.77 | KDM4E (0.59) | GABRA1GABRA5GABRB2KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL1430093 | 0.77 | KDM4E (0.69) | GABRA1GABRA5GABRB2KDM4ENPC1 | |
| SCHEMBL1431043 | 0.77 | KDM4E (0.69) | GABRA1GABRA5GABRB2KDM4ENPC1 | |
| SCHEMBL7228643 | 0.77 | KDM4E (0.64) | KDM4ENPC1POLBHTTRAB9A | |
| SCHEMBL7231135 | 0.77 | KDM4E (0.58) | KDM4ENPC1POLBHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6514969-B2 | Alzheimer's diseas, Parkinson disease, Huntington disease | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-02-04 | — | — | US | disclosed |
| US-20020042420-A1 | Beta-amyloid inhibitors, processes for preparing them, and their use in pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020042420-A1 | Beta-amyloid inhibitors, processes for preparing them, and their use in pharmaceutical compositions | HTT, APP, BACE1 | GABRA1 2063/4885GABRA5 2528/4885GABRB2 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.