Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 2/20 | 0.60 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.60 |
| ▸ | TACR1 | P25103 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | TSPO | P30536 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150 | 0.86 | GABRA2 (0.70) | GABRA2GABRB2ALDH1A1NR1I2ABCB11 | |
| SCHEMBL3028009 | 0.81 | TSPO (0.69) | GABRA2GABRB2ALDH1A1NR1I2ABCB11 | |
| SCHEMBL23624275 | 0.81 | TSPO (0.69) | GABRA2GABRB2ALDH1A1NR1I2ABCB11 | |
| SCHEMBL1691241 | 0.80 | ALDH1A1 (0.68) | GABRA2GABRB2ALDH1A1NR1I2ABCB11 | |
| SCHEMBL7261 | 0.80 | GABRA2 (0.68) | GABRA2GABRB2ALDH1A1NR1I2ABCB11 | |
| SCHEMBL23624274 | 0.79 | ALDH1A1 (0.56) | GABRA2GABRB2ALDH1A1NR1I2ABCB11 | |
| SCHEMBL23624269 | 0.78 | TSPO (0.88) | GABRA2GABRB2NR1I2ABCB11ALB | |
| SCHEMBL7222018 | 0.78 | GABRA1 (0.59) | GABRB2SLC2A1KDM4EHTT | |
| Hydrochloric Acid SCHEMBL1429987 | 0.77 | ALDH1A1 (0.68) | GABRA2GABRB2ALDH1A1NR1I2ABCB11 | |
| SCHEMBL3036910 | 0.77 | TSPO (0.59) | GABRA2GABRB2ALDH1A1NR1I2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4501745-A | TREATMENT OF NERVOUS SYSTEM DISORDERS | SYNTHELABO (FR) | 1985-02-26 | — | — | US | disclosed |