SCHEMBL8553384

SCHEMBL8553384

CC(C)(C)C(=O)OCC(=O)C(=O)Cl

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.38
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7222887 0.81 PRKCA (0.41) PRKCAPOLBGAANPSR1ELANE
SCHEMBL3517297 0.78 PRKCA (0.42) PRKCAPOLBGAANPSR1ELANE
SCHEMBL9035448 0.77 PRKCA (0.38) PRKCAPOLBGAANPSR1ELANE
SCHEMBL28019636 0.75 PRKCA (0.43) PRKCAPOLBGAANPSR1ELANE
SCHEMBL13647509 0.73 MAPK1 (0.47) PRKCAPOLBGAANPSR1ELANE
SCHEMBL8816807 0.73 PRKCA (0.42) PRKCAPOLBGAANPSR1ELANE
SCHEMBL9866275 0.73 PRKCA (0.42) PRKCAPOLBGAANPSR1ELANE
SCHEMBL9311644 0.73 ALDH1A1 (0.43) GAA
SCHEMBL7089654 0.73 PRKCA (0.42) PRKCAPOLBGAANPSR1ELANE
SCHEMBL9871939 0.71 PRKCA (0.41) PRKCAPOLBGAANPSR1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0559533-B1 Process for preparing beta-lactam derivative and synthetic intermediate thereof TANABE SEIYAKU CO (JP) 1998-07-22 EP disclosed
US-5589592-A Process for preparing β-lactam derivative and synthetic intermediate TANABE SEIYAKU CO., LTD. (JP) 1996-12-31 US disclosed
US-5414081-A Treating a 1-aza-3-thiabicycloalkane with base and phosphine or phosphite desulfurizing agent, and reacting the product with an active esterifying agent TANABE SEIYAKU CO., LTD. (JP) 1995-05-09 US disclosed
EP-0559533-A1 Process for preparing beta-lactam derivative and synthetic intermediate thereof TANABE SEIYAKU CO., LTD. (JP) 1993-09-08 EP disclosed