Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 4/20 | 0.64 |
| ▸ | FGF1 | P05230 | 1/20 | 0.54 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | RHOA | P61586 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240628 | 0.94 | CASP6 (0.72) | CASP6FGF1TIMP3CTDSP1RHOA | |
| SCHEMBL6243020 | 0.89 | CASP6 (0.66) | CASP6FGF1TIMP3CTDSP1RHOA | |
| SCHEMBL11597730 | 0.87 | CASP6 (0.56) | CASP6FGF1TIMP3CTDSP1CYP2C9 | |
| SCHEMBL4119552 | 0.85 | CASP6 (0.67) | CASP6FGF1TIMP3CTDSP1RHOA | |
| SCHEMBL7231212 | 0.84 | CASP6 (0.75) | CASP6FGF1TIMP3RHOAALOX5 | |
| SCHEMBL7222842 | 0.84 | ALOX5 (0.68) | CASP6FGF1TIMP3CTDSP1ALOX5 | |
| SCHEMBL7233377 | 0.84 | CASP6 (0.60) | CASP6FGF1TIMP3CTDSP1RHOA | |
| SCHEMBL6242889 | 0.83 | CASP6 (0.57) | CASP6FGF1TIMP3ALOX5CYP2C9 | |
| SCHEMBL7223972 | 0.82 | FGF1 (0.63) | CASP6FGF1TIMP3RHOAALOX5 | |
| SCHEMBL7224393 | 0.82 | CASP6 (0.58) | CASP6FGF1TIMP3RHOACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653321-B1 | Stimulating kinase activity of insulin receptor; type II diabetes; hyperglycemia | TELIK, INC. | 2003-11-25 | — | — | US | disclosed |
| EP-1200396-A1 | NAPHTHYLSULFONIC ACIDS AND RELATED COMPOUNDS AS GLUCOSE UPTAKE AGONISTS | TELIK, INC. (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001012591-A1 | NOVEL NAPHTHYLSULFONIC ACIDS AND RELATED COMPOUNDS AS GLUCOSE UPTAKE AGONISTS | TELIK, INC. (US) | 2001-02-22 | — | — | WO | disclosed |