Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.96 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CCR1 | P32246 | 5/20 | 0.60 |
| ▸ | CCR8 | P51685 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.60 |
| ▸ | CCR5 | P51681 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | MMP2 | P08253 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249178 | 1.00 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL723791 | 1.00 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL6513577 | 0.98 | LMNA (1.00) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL8313 | 0.98 | LMNA (1.00) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL1052095 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL15788918 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| Hydrochloric Acid SCHEMBL4917361 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| Iodide SCHEMBL10638043 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL7268962 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL3885158 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9157884-B2 | Method for electrochemically detecting target substance, method for electrochemically detecting analyte, and detection set | SYSMEX CORPORATION (JP) | 2015-10-13 | — | — | US | disclosed |
| EP-2515112-B1 | Method for electrochemically detecting analyte | SYSMEX CORP (JP) | 2015-08-12 | — | — | EP | disclosed |
| US-20140371082-A1 | PROCESS AND APPARATUS FOR QUANTIFYING NUCLEIC ACID IN A SAMPLE | BIOQUANTA SA (FR) | 2014-12-18 | — | — | US | disclosed |
| US-20120267258-A1 | METHOD FOR ELECTROCHEMICALLY DETECTING ANALYTE | NARA INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) | 2012-10-25 | — | — | US | disclosed |
| EP-2515112-A2 | Method for electrochemically detecting analyte | SYSMEX CORPORATION (JP) | 2012-10-24 | — | — | EP | disclosed |
| US-20120048747-A1 | METHOD FOR ELECTROCHEMICALLY DETECTING TARGET SUBSTANCE, METHOD FOR ELECTROCHEMICALLY DETECTING ANALYTE, AND DETECTION SET | SYSMEX CORPORATION (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20090036315-A1 | Device and methods for detecting and quantifying one or more target agents | ANTARA BIOSCIENCES INC. (US) | 2009-02-05 | — | — | US | disclosed |
| EP-1146331-B1 | GENE DETECTING CHIP, DETECTOR, AND DETECTING METHOD | TAKENAKA SHIGEORI (JP) | 2008-09-10 | — | — | EP | disclosed |
| US-20080026394-A1 | Methods of detecting one or more cancer markers | ANTARA BIOSCIENCES INC. (US) | 2008-01-31 | — | — | US | disclosed |
| US-6916614-B1 | For detecting and analyzing genetic abnormalities such as DNA single base substitution SNP (single nucleotide polymorphism), plural base substitution, point mutation, and genetic loss as well as addition of base sequences in genes | TUM GENE, INC. (JP) | 2005-07-12 | — | — | US | disclosed |
| US-6864055-B2 | Method for detecting nucleic acids | FUJI PHOTO FILM CO., LTD. (JP) | 2005-03-08 | — | — | US | disclosed |
| US-20040152097-A1 | using solid phase synthesis for quantitative analysis with high sensitivity and enhanced throughput; genetic engineering | TOPPAN PRINTING CO., LTD. (JP) | 2004-08-05 | — | — | US | disclosed |
| US-20040152085-A1 | Surface for collection and/or purification of nucleic acids | VERIDIAN SYSTEMS DIVISION | 2004-08-05 | — | — | US | disclosed |
| US-20020076717-A1 | Method for detecting nucleic acids | FUJI PHOTO FILM CO., LTD. (JP) | 2002-06-20 | — | — | US | disclosed |
| US-20010053522-A1 | DNA chip and reactive electrode | FUJI PHOTO FILM CO., LTD. | 2001-12-20 | — | — | US | disclosed |
| EP-1146331-A1 | GENE DETECTING CHIP, DETECTOR, AND DETECTING METHOD | Takenaka, Shigeori (JP) | 2001-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020076717-A1 | Method for detecting nucleic acids | POLRMT, DNMT1, POLN | LMNA 440/4885CYP3A4 4526/4885CCR1 3781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.