Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | UGCG | Q16739 | 1/20 | 0.37 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220749 | 0.89 | PKM (0.46) | ALDH1A1KMT2AMEN1HTTUGCG | |
| SCHEMBL7229707 | 0.84 | SMN1; SMN2 (0.44) | HTTUGCGHTR1ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7228991 | 0.83 | SMN1; SMN2 (0.44) | HTTUGCGHTR1ADRD2DRD4 | |
| SCHEMBL7223904 | 0.83 | SMN1; SMN2 (0.46) | HTTUGCGDRD2DRD4 | |
| SCHEMBL7229703 | 0.82 | UGCG (0.39) | ALDH1A1KMT2AMEN1HTTUGCG | |
| Hydrochloric Acid SCHEMBL7228986 | 0.81 | UGCG (0.39) | ALDH1A1KMT2AMEN1HTTUGCG | |
| SCHEMBL7223901 | 0.81 | UGCG (0.39) | ALDH1A1KMT2AMEN1HTTUGCG | |
| SCHEMBL7223351 | 0.80 | TAS1R3 (0.44) | ALDH1A1KMT2AMEN1HTTUGCG | |
| SCHEMBL7224992 | 0.78 | ADRB3 (0.42) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL7221545 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1HTTUGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610705-B1 | Treating breast cancer, osteoporosis, hypercholesteremia or endometriosis | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-08-26 | — | — | US | disclosed |