Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 6/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | UGCG | Q16739 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7224992 | 0.91 | ADRB3 (0.42) | ADRB3ADRB2ADRB1ALDH1A1HTT | |
| SCHEMBL7220715 | 0.85 | KDM4E (0.48) | ALDH1A1HTTKMT2AMEN1UGCG | |
| SCHEMBL13719534 | 0.78 | ADRB3 (0.68) | ADRB3ADRB2ADRB1ALDH1A1HTT | |
| SCHEMBL7221545 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HTTKMT2AMEN1UGCG | |
| SCHEMBL7220749 | 0.74 | PKM (0.46) | ALDH1A1HTTKMT2AMEN1TP53 | |
| SCHEMBL7223322 | 0.73 | PSMB1 (0.52) | ALDH1A1KMT2AMEN1UGCG | |
| SCHEMBL11748513 | 0.73 | UGCG (0.44) | ALDH1A1HTTKMT2AMEN1UGCG | |
| Hydrochloric Acid SCHEMBL7223567 | 0.72 | PSMB1 (0.51) | ALDH1A1KMT2AMEN1UGCG | |
| SCHEMBL7223883 | 0.72 | PSMB1 (0.54) | ALDH1A1KMT2AMEN1UGCG | |
| SCHEMBL7223982 | 0.71 | MAPT (0.50) | ADRB3ADRB2ADRB1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610705-B1 | Treating breast cancer, osteoporosis, hypercholesteremia or endometriosis | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-08-26 | — | — | US | claimed |
| US-6610705-B1 | Treating breast cancer, osteoporosis, hypercholesteremia or endometriosis | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-08-26 | — | — | US | disclosed |