Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | UGCG | Q16739 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223605 | 0.85 | ADRB3 (0.46) | KDM4EKMT2AMEN1UGCGHTT | |
| SCHEMBL7224992 | 0.77 | ADRB3 (0.42) | KDM4EKMT2AMEN1UGCGHTT | |
| SCHEMBL7221545 | 0.77 | ALDH1A1 (0.46) | KMT2AMEN1UGCGHTTALDH1A1 | |
| SCHEMBL7220749 | 0.75 | PKM (0.46) | TDP1KMT2AMEN1UGCGHTT | |
| SCHEMBL7223322 | 0.74 | PSMB1 (0.52) | KMT2AMEN1UGCGALDH1A1 | |
| SCHEMBL7223883 | 0.73 | PSMB1 (0.54) | KMT2AMEN1UGCGALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL7223567 | 0.73 | PSMB1 (0.51) | TDP1KMT2AMEN1UGCGALDH1A1 | |
| SCHEMBL7229768 | 0.73 | KDM4E (0.48) | KDM4EMAPK1TDP1KMT2AMEN1 | |
| SCHEMBL7223351 | 0.72 | TAS1R3 (0.44) | KMT2AMEN1UGCGHTTALDH1A1 | |
| SCHEMBL7223321 | 0.70 | UGCG (0.44) | KMT2AMEN1UGCGHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610705-B1 | Treating breast cancer, osteoporosis, hypercholesteremia or endometriosis | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-08-26 | — | — | US | disclosed |