Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229535 | 0.90 | SLC6A4 (0.40) | SLC6A3 | |
| SCHEMBL7225185 | 0.90 | HTR3E (0.36) | SLC6A3KCNH2 | |
| SCHEMBL7124789 | 0.85 | MMP2 (0.36) | SLC6A3 | |
| SCHEMBL7223246 | 0.84 | SLC6A3 (0.40) | SLC6A3KCNH2SMN1; SMN2 | |
| SCHEMBL7127379 | 0.82 | MMP2 (0.36) | — | |
| SCHEMBL7121780 | 0.80 | SLC6A3 (0.46) | SLC6A3KCNH2SMN1; SMN2 | |
| SCHEMBL7225195 | 0.80 | SLC6A3 (0.38) | SLC6A3GHSRLMNA | |
| SCHEMBL7118083 | 0.80 | SMN1; SMN2 (0.38) | SLC6A3SMN1; SMN2KDM1A | |
| SCHEMBL7124235 | 0.80 | MMP2 (0.36) | SLC6A3 | |
| Hydrochloric Acid SCHEMBL7124074 | 0.79 | SLC6A3 (0.45) | SLC6A3KCNH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |