Sugi Predict

Sugi Predict / Compounds / SCHEMBL722393

SCHEMBL722393

SCHEMBL722393

C[C@H](N)C(=O)OCCC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GRIN2D O15399 1/20 0.41
▸ GRIN3B O60391 1/20 0.41
▸ GRIN1 Q05586 1/20 0.41
▸ GRIN2A Q12879 1/20 0.41
▸ GRIN2B Q13224 1/20 0.41
▸ GRIN2C Q14957 1/20 0.41
▸ GRIN3A Q8TCU5 1/20 0.41
▸ CYP3A4 P08684 2/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ CYP2D6 P10635 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ NFKB1 P19838 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37
▸ LMNA P02545 2/20 0.36
▸ PMP22 Q01453 1/20 0.36
▸ NLRP3 Q96P20 1/20 0.36
▸ CHRNB2 P17787 1/20 0.34
▸ CHRNB4 P30926 1/20 0.34
▸ CHRNA3 P32297 1/20 0.34
▸ CHRNA4 P43681 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL722392 1.00 GRIN2D (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Hydrochloric Acid SCHEMBL23827991 0.98 GRIN2D (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Hydrochloric Acid SCHEMBL23827992 0.98 GRIN2D (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL14296190 0.88 GRIN2D (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL14296188 0.88 GRIN2D (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL17476703 0.83 SLC7A5 (0.38) LNPEP
SCHEMBL17231632 0.83 SLC7A5 (0.38) LNPEP
SCHEMBL19472066 0.83 SLC7A5 (0.38) LNPEP
SCHEMBL10044939 0.82 EGFR (0.33) —
SCHEMBL30269837 0.82 GRIN2D (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035394-A1 1`-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF GILEAD SCIENCES INC (US) 2026-02-05 — — US disclosed
US-12404289-B2 1′-cyano nucleoside analogs and uses thereof GILEAD SCIENCES, INC. (US) 2025-09-02 — — US disclosed
CN-115175735-B Antiviral compounds 吉利德科学公司 2025-03-04 — — CN disclosed
CN-118598916-A Antiviral compounds 吉利德科学公司 2024-09-06 — — CN disclosed
US-20240287109-A1 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF GILEAD SCIENCES, INC. 2024-08-29 — — US disclosed
US-12030903-B2 Antiviral compounds GILEAD SCIENCES, INC. (US) 2024-07-09 — — US disclosed
CN-115135383-B Antiviral compounds 吉利德科学公司 2024-06-11 — — CN disclosed
US-11939347-B2 1′-cyano nucleoside analogs and uses thereof GILEAD SCIENCES, INC. (US) 2024-03-26 — — US disclosed
US-20230382931-A1 DIOXOLANE ANALOGUES OF URIDINE FOR THE TREATMENT OF CANCER MEDIVIR AB (SE) 2023-11-30 — — US disclosed
US-20230295201-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2023-09-21 — — US disclosed
US-20140066398-A1 HCV POLYMERASE INHIBITORS MEDIVIR, AB (SE) 2014-03-06 — — US disclosed
US-20140066398-A1 HCV POLYMERASE INHIBITORS MEDIVIR, AB (SE) 2014-03-06 — — US disclosed
US-20140066398-A1 HCV POLYMERASE INHIBITORS MEDIVIR, AB (SE) 2014-03-06 — — US disclosed
WO-2013084165-A1 HCV POLYMERASE INHIBITORS MEDIVIR AB (SE) 2013-06-13 — — WO disclosed
WO-2013084165-A1 HCV POLYMERASE INHIBITORS MEDIVIR AB (SE) 2013-06-13 — — WO disclosed
US-20130143835-A1 HCV Polymerase Inhibitors MEDIVIR AB (SE) 2013-06-06 — — US disclosed
US-20130143835-A1 HCV Polymerase Inhibitors MEDIVIR AB (SE) 2013-06-06 — — US disclosed
US-20130143835-A1 HCV Polymerase Inhibitors MEDIVIR AB (SE) 2013-06-06 — — US disclosed
US-20120052046-A1 Phosphoramidate Derivatives of Guanosine Nucleoside Compunds for Treatment of Viral Infections UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2012-03-01 — — US disclosed
CN-102348712-A Phosphoramidate derivatives of guanosine nucleoside compounds for treatment of viral infections UNIV CARDIFF 2012-02-08 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295201-A1 ANTIVIRAL COMPOUNDS MAVS, HAVCR2, ZC3HAV1 GRIN2D 4821/4885GRIN3B 3774/4885GRIN1 4475/4885
US-20120052046-A1 Phosphoramidate Derivatives of Guanosine Nucleoside Compunds for Treatment of Viral Infections PNP, SAMHD1, MTAP GRIN2D 4396/4885GRIN3B 1862/4885GRIN1 2319/4885
US-12030903-B2 Antiviral compounds EIF2AK2, MAVS, DUT GRIN2D 4594/4885GRIN3B 4000/4885GRIN1 4723/4885
US-20130143835-A1 HCV Polymerase Inhibitors POLI, HAVCR2, EIF2AK2 GRIN2D 4837/4885GRIN3B 4727/4885GRIN1 4635/4885
US-20240287109-A1 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF TYMP, PNP, DUT GRIN2D 4720/4885GRIN3B 3166/4885GRIN1 3100/4885
US-12404289-B2 1′-cyano nucleoside analogs and uses thereof TYMP, PNP, DUT GRIN2D 4694/4885GRIN3B 3063/4885GRIN1 3111/4885
US-20140066398-A1 HCV POLYMERASE INHIBITORS POLI, HAVCR2, EIF2AK2 GRIN2D 4837/4885GRIN3B 4727/4885GRIN1 4635/4885
US-11939347-B2 1′-cyano nucleoside analogs and uses thereof TYMP, PNP, DUT GRIN2D 4694/4885GRIN3B 3063/4885GRIN1 3111/4885
US-20260035394-A1 1`-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF PNP, SLC28A1, SLC29A1 GRIN2D 2409/4885GRIN3B 4099/4885GRIN1 2627/4885
US-20230382931-A1 DIOXOLANE ANALOGUES OF URIDINE FOR THE TREATMENT OF CANCER ADORA3, DUT, NTPCR GRIN2D 4564/4885GRIN3B 3121/4885GRIN1 3430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.