Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 4/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | FGF1 | P05230 | 1/20 | 0.56 |
| ▸ | DDX3X | O00571 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.48 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.48 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223972 | 0.89 | FGF1 (0.63) | TIMP3CASP6FGF1MEN1KMT2A | |
| SCHEMBL7225097 | 0.89 | TIMP3 (0.58) | TIMP3CASP6FGF1MEN1KMT2A | |
| SCHEMBL7234616 | 0.89 | FGF1 (0.62) | TIMP3CASP6FGF1MEN1KMT2A | |
| SCHEMBL7233875 | 0.88 | CASP6 (0.57) | TIMP3CASP6FGF1MEN1KMT2A | |
| SCHEMBL7224576 | 0.88 | TIMP3 (0.57) | TIMP3CASP6FGF1MEN1KMT2A | |
| SCHEMBL7232738 | 0.87 | HPGD (0.55) | TIMP3CASP6FGF1MEN1KMT2A | |
| SCHEMBL7233377 | 0.85 | CASP6 (0.60) | TIMP3CASP6FGF1MEN1KMT2A | |
| SCHEMBL7231212 | 0.85 | CASP6 (0.75) | TIMP3CASP6FGF1MEN1KMT2A | |
| SCHEMBL7226724 | 0.84 | FGF1 (0.62) | TIMP3CASP6FGF1MEN1KMT2A | |
| SCHEMBL7222503 | 0.84 | TIMP3 (0.58) | TIMP3CASP6FGF1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653321-B1 | Stimulating kinase activity of insulin receptor; type II diabetes; hyperglycemia | TELIK, INC. | 2003-11-25 | — | — | US | disclosed |