Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7224265 | 0.99 | HPGD (0.43) | HPGDMAPTKDM4ELMNANPC1 | |
| SCHEMBL7226017 | 0.92 | MAPT (0.46) | HPGDMAPTKDM4ELMNANPC1 | |
| SCHEMBL7234830 | 0.83 | RAB9A (0.42) | MAPTLMNANPC1RAB9AGAA | |
| SCHEMBL7224300 | 0.83 | RAB9A (0.40) | HPGDMAPTKDM4ELMNANPC1 | |
| SCHEMBL7072612 | 0.83 | RAB9A (0.49) | HPGDMAPTKDM4ELMNANPC1 | |
| SCHEMBL7225840 | 0.83 | RAB9A (0.41) | HPGDMAPTKDM4ELMNANPC1 | |
| SCHEMBL7233102 | 0.83 | ALDH1A1 (0.49) | HPGDMAPTKDM4ELMNANPC1 | |
| SCHEMBL7231145 | 0.83 | SLC9A1 (0.44) | LMNANPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL7226764 | 0.83 | RAB9A (0.53) | HPGDMAPTKDM4ELMNANPC1 | |
| SCHEMBL7223842 | 0.82 | MAPKAPK2 (0.45) | HPGDMAPTKDM4ELMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |