Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7226523 | 0.90 | SMN1; SMN2 (0.42) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL7234830 | 0.88 | RAB9A (0.42) | LMNAMAPTMAPK1MEN1RECQL | |
| SCHEMBL7224300 | 0.87 | RAB9A (0.40) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL7223501 | 0.87 | RAB9A (0.40) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL7232158 | 0.87 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL7225840 | 0.87 | RAB9A (0.41) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL7231145 | 0.87 | SLC9A1 (0.44) | LMNASLC9A1NPC1RAB9AHTR3E | |
| SCHEMBL7072612 | 0.87 | RAB9A (0.49) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL7226764 | 0.87 | RAB9A (0.53) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL7233101 | 0.86 | RAB9A (0.39) | ALDH1A1HPGDKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |