Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 8/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7230686 | 0.90 | CYP2C19 (0.35) | F10MAPTLMNAMEN1KMT2A | |
| SCHEMBL7231963 | 0.85 | ESR1 (0.37) | ALDH1A1RAB9ANPC1 | |
| SCHEMBL7232904 | 0.85 | MITF (0.38) | F10MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7120596 | 0.84 | CHRNA7 (0.36) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7224982 | 0.84 | CHRNA7 (0.44) | F10MAPTLMNAMEN1KMT2A | |
| SCHEMBL7232207 | 0.83 | SLC6A2 (0.39) | RAB9ANPC1 | |
| SCHEMBL7224995 | 0.83 | CHRNA7 (0.34) | ALDH1A1 | |
| SCHEMBL7234021 | 0.83 | SLC6A3 (0.39) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7231965 | 0.83 | CHRNA7 (0.36) | — | |
| Hydrochloric Acid SCHEMBL7231366 | 0.82 | SLC6A3 (0.38) | MAPTMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |