Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7234113 | 0.89 | PTPN11 (0.41) | SLC6A3LMNAALDH1A1MAPTSLC6A2 | |
| SCHEMBL7230851 | 0.89 | CHRNA7 (0.35) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7231968 | 0.88 | ALDH1A1 (0.42) | SLC6A3LMNAALDH1A1MAPTSLC6A2 | |
| SCHEMBL7225901 | 0.83 | PTPN11 (0.42) | LMNAALDH1A1MAPTCYP2C19KMT2A | |
| SCHEMBL7115230 | 0.83 | CHRNA7 (0.35) | SLC6A3ALDH1A1MAPTSLC6A2SLC6A4 | |
| SCHEMBL7225963 | 0.82 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7225781 | 0.82 | PTPN11 (0.44) | SLC6A3LMNAALDH1A1MAPTSLC6A2 | |
| SCHEMBL7072340 | 0.81 | PTPN1 (0.46) | SLC6A3LMNAALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL7074856 | 0.81 | PTPN1 (0.46) | SLC6A3LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL7232031 | 0.80 | PTPN11 (0.43) | SLC6A3LMNAALDH1A1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |