Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | FGF1 | P05230 | 1/20 | 0.51 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7233931 | 0.97 | CASP6 (0.57) | PTGESCASP6FGF1TIMP3CYP1A2 | |
| SCHEMBL7231411 | 0.92 | CASP6 (0.52) | PTGESCASP6FGF1TIMP3CYP1A2 | |
| SCHEMBL7223935 | 0.91 | CASP6 (0.51) | PTGESCASP6FGF1TIMP3CYP1A2 | |
| SCHEMBL7233377 | 0.89 | CASP6 (0.60) | PTGESCASP6FGF1TIMP3NPC1 | |
| SCHEMBL7233109 | 0.89 | FGF1 (0.59) | PTGESCASP6FGF1TIMP3NPC1 | |
| SCHEMBL7231701 | 0.88 | CASP6 (0.56) | PTGESCASP6FGF1TIMP3NPC1 | |
| SCHEMBL7224393 | 0.87 | CASP6 (0.58) | PTGESCASP6FGF1TIMP3NPC1 | |
| SCHEMBL7222503 | 0.87 | TIMP3 (0.58) | PTGESCASP6FGF1TIMP3NPC1 | |
| SCHEMBL7224369 | 0.86 | CASP6 (0.57) | PTGESCASP6FGF1TIMP3NPC1 | |
| SCHEMBL7233849 | 0.86 | CASP6 (0.70) | PTGESCASP6FGF1TIMP3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653321-B1 | Stimulating kinase activity of insulin receptor; type II diabetes; hyperglycemia | TELIK, INC. | 2003-11-25 | — | — | US | disclosed |
| EP-1200396-A1 | NAPHTHYLSULFONIC ACIDS AND RELATED COMPOUNDS AS GLUCOSE UPTAKE AGONISTS | TELIK, INC. (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001012591-A1 | NOVEL NAPHTHYLSULFONIC ACIDS AND RELATED COMPOUNDS AS GLUCOSE UPTAKE AGONISTS | TELIK, INC. (US) | 2001-02-22 | — | — | WO | disclosed |